Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | MMP14 | P50281 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2186346 | 0.76 | CA12 (0.48) | MAPTKDM4EALDH1A1SMN1; SMN2LMNA | |
| Fluorobenzene SCHEMBL27883519 | 0.67 | TSHR (0.51) | MAPTKDM4ECYP3A4ALDH1A1KMT2A | |
| SCHEMBL506690 | 0.66 | IDO1 (0.42) | ACHEALDH1A1 | |
| SCHEMBL1681746 | 0.64 | ALDH1A1 (0.52) | MAPTKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL6203754 | 0.64 | PHGDH (0.48) | MAPTALDH1A1KMT2ASMN1; SMN2L3MBTL1 | |
| Fluorobenzene SCHEMBL27883526 | 0.63 | KMT2A (0.40) | MAPTALDH1A1KMT2APKM | |
| SCHEMBL19976621 | 0.63 | P2RX7 (0.50) | MAPTKDM4EACHECYP3A4ALDH1A1 | |
| SCHEMBL2769910 | 0.62 | POLB (0.73) | MAPTALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL10231108 | 0.62 | ACHE (0.53) | MAPTKDM4EACHECYP3A4ALDH1A1 | |
| Ethane SCHEMBL27588936 | 0.62 | KMT2A (0.35) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101351452-A | HIV integrase inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2009-01-21 | — | — | CN | disclosed |