Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28329509 | 0.85 | NOTUM (0.41) | NOTUMTRPV1MGLLARGABRA2 | |
| SCHEMBL20181201 | 0.81 | F11 (0.42) | NOTUMARGABRA2GABRB2 | |
| SCHEMBL26031187 | 0.81 | FLT3 (0.53) | ALDH1A1NOTUMTRPV1ARGABRA2 | |
| SCHEMBL21849514 | 0.80 | TRPV1 (0.43) | AMY1AAPPNOTUMTRPV1MGLL | |
| SCHEMBL21849198 | 0.78 | TRPV1 (0.43) | AMY1AAPPNOTUMTRPV1AR | |
| SCHEMBL28600542 | 0.77 | P2RX7 (0.38) | AMY1ANOTUMTRPV1MGLLKCNN4 | |
| SCHEMBL21816177 | 0.76 | MYC (0.46) | ALDH1A1NOTUMMGLL | |
| SCHEMBL28107702 | 0.73 | AR (0.44) | NOTUMARRXRAGRIN1GRIN2B | |
| SCHEMBL18367585 | 0.72 | TRPV1 (0.49) | ALDH1A1AMY1AAPPTRPV1KCNN4 | |
| SCHEMBL30332311 | 0.72 | CYP1A2 (0.46) | NOTUMARRXRAGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065614-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |