Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | SELE | P16581 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.35 |
| ▸ | CLK2 | P49760 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3795260 | 0.76 | MAPT (0.49) | MAPTNPSR1KMT2ASMN1; SMN2HTT | |
| SCHEMBL30323242 | 0.73 | MAPT (0.53) | MAPTNPSR1KMT2ASMN1; SMN2HTT | |
| SCHEMBL438061 | 0.73 | MAPT (0.53) | MAPTNPSR1KMT2ASMN1; SMN2HTT | |
| SCHEMBL14968875 | 0.72 | MAPT (0.49) | MAPTNPSR1KMT2ASMN1; SMN2HTT | |
| SCHEMBL2185553 | 0.72 | MAPT (0.56) | MAPTNPSR1KMT2ASMN1; SMN2HTT | |
| SCHEMBL868188 | 0.71 | MAPT (0.60) | MAPTNPSR1KMT2ASMN1; SMN2HTT | |
| SCHEMBL900339 | 0.70 | MAPT (0.43) | MAPTNPSR1KMT2ASMN1; SMN2HTT | |
| SCHEMBL899715 | 0.69 | MAPT (0.53) | MAPTNPSR1KMT2ASMN1; SMN2HTT | |
| SCHEMBL14293290 | 0.69 | MAPT (0.53) | MAPTNPSR1KMT2ASMN1; SMN2HTT | |
| SCHEMBL2185527 | 0.69 | SMN1; SMN2 (0.58) | MAPTNPSR1KMT2ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8008487-B2 | Substituted thieno[2,3-D]pyrimidines as fungicides | DOW AGROSCIENCES LLC (US) | 2011-08-30 | — | — | US | disclosed |
| EP-1802632-B1 | THIENO-PYRIMIDINE COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2011-07-13 | — | — | EP | disclosed |
| EP-1802632-A1 | THIENO-PYRIMIDINE COMPOUNDS HAVING FUNGICIDAL ACTIVITY | Dow AgroSciences LLC (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006047397-A1 | THIENO-PYRIMIDINE COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2006-05-04 | — | — | WO | disclosed |
| US-20060089370-A1 | Thieno-pyrimidine compounds having fungicidal activity | BREWSTER WILLIAM K | 2006-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089370-A1 | Thieno-pyrimidine compounds having fungicidal activity | TYMP, DPM1, TYMS | MAPT 2484/4885NPSR1 4180/4885KMT2A 2814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.