Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | OTC | P00480 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DDAH1 | O94760 | 3/20 | 0.37 |
| ▸ | NPY4R | P50391 | 7/20 | 0.36 |
| ▸ | NPY1R | P25929 | 5/20 | 0.36 |
| ▸ | NPY2R | P49146 | 4/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2186467 | 1.00 | DPP7 (0.39) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL19465128 | 0.86 | DPP7 (0.39) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL5872308 | 0.86 | DPP7 (0.39) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL18819440 | 0.84 | DPP7 (0.45) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL30531668 | 0.84 | OTC (0.41) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL9194730 | 0.84 | DPP7 (0.45) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL22799242 | 0.84 | NPY4R (0.38) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL22799243 | 0.84 | NPY4R (0.38) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL21027152 | 0.84 | DPP7 (0.45) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL1162684 | 0.84 | DPP7 (0.40) | DPP7OTCALOX15MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105664252-B | The improvement of fixed biological entities | W.L.戈尔及同仁股份有限公司 | 2019-11-19 | — | — | CN | disclosed |
| CN-102458304-B | Self-expanding stent with polygonal transition zone | 奥巴斯尼茨医学公司 | 2016-07-06 | — | — | CN | disclosed |
| US-20110166063-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NEKTAR THERAPEUTICS (US) | 2011-07-07 | — | — | US | disclosed |
| EP-0377583-A4 | PROTEINASE INHIBITORS FOR TREATMENT OF GASTROINTESTINAL ULCER DISEASE | — | 1990-09-05 | — | — | EP | disclosed |
| EP-0377583-A1 | PROTEINASE INHIBITORS FOR TREATMENT OF GASTROINTESTINAL ULCER DISEASE | BRIGHAM AND WOMEN'S HOSPITAL (US) | 1990-07-18 | — | — | EP | disclosed |
| US-4891356-A | Proteinase inhibitors for treatment of gastrointestinal ulcer disease | BRIGHAM & WOMEN'S HOSPITAL (US) | 1990-01-02 | — | — | US | disclosed |
| WO-1989000426-A1 | PROTEINASE INHIBITORS FOR TREATMENT OF GASTROINTESTINAL ULCER DISEASE | BRIGHAM AND WOMEN'S HOSPITAL (US) | 1989-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166063-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NGLY1, CD44, IAPP | DPP7 450/4885OTC 1454/4885ALOX15 3830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.