Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.45 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
| ▸ | NPY4R | P50391 | 7/20 | 0.39 |
| ▸ | NPY1R | P25929 | 5/20 | 0.39 |
| ▸ | NPY2R | P49146 | 4/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.39 |
| ▸ | RRM1 | P23921 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | OTC | P00480 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21027152 | 1.00 | DPP7 (0.45) | DPP7GNAI3GNAO1GNAI1NPY4R | |
| SCHEMBL18819440 | 1.00 | DPP7 (0.45) | DPP7GNAI3GNAO1GNAI1NPY4R | |
| Hydrochloric Acid SCHEMBL28913679 | 0.98 | DPP7 (0.44) | DPP7GNAI3GNAO1GNAI1NPY4R | |
| Hydrochloric Acid SCHEMBL28913681 | 0.98 | DPP7 (0.44) | DPP7GNAI3GNAO1GNAI1NPY4R | |
| Hydrochloric Acid SCHEMBL29065758 | 0.98 | DPP7 (0.44) | DPP7GNAI3GNAO1GNAI1NPY4R | |
| Hydrochloric Acid SCHEMBL29065757 | 0.98 | DPP7 (0.44) | DPP7GNAI3GNAO1GNAI1NPY4R | |
| SCHEMBL18868717 | 0.89 | DPP7 (0.36) | DPP7GNAI3GNAO1GNAI1NPY4R | |
| SCHEMBL13660193 | 0.87 | DPP7 (0.50) | DPP7GNAI3GNAO1GNAI1NPY4R | |
| SCHEMBL2186467 | 0.84 | DPP7 (0.39) | DPP7GNAI3GNAO1GNAI1NPY4R | |
| SCHEMBL19465128 | 0.84 | DPP7 (0.39) | DPP7GNAI3GNAO1GNAI1NPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115466219-B | Preparation method of 1- [3- (2-amino-4-ethyl-1H-imidazol-5-yl) propyl ] guanidine | 中国科学院天津工业生物技术研究所 | 2023-09-08 | — | — | CN | claimed |
| CN-115466219-A | Preparation method of 1- [3- (2-amino-4-ethyl-1H-imidazole-5-yl) propyl ] guanidine | 中国科学院天津工业生物技术研究所 | 2022-12-13 | — | — | CN | claimed |
| CN-115466219-B | Preparation method of 1- [3- (2-amino-4-ethyl-1H-imidazol-5-yl) propyl ] guanidine | 中国科学院天津工业生物技术研究所 | 2023-09-08 | — | — | CN | disclosed |
| US-11717532-B2 | Methods and compositions for treating wounds utilizing chitosan compounds | SYNEDGEN, INC. (US) | 2023-08-08 | — | — | US | disclosed |
| CN-115466219-A | Preparation method of 1- [3- (2-amino-4-ethyl-1H-imidazole-5-yl) propyl ] guanidine | 中国科学院天津工业生物技术研究所 | 2022-12-13 | — | — | CN | disclosed |
| US-11433092-B2 | Compositions and methods of use for wound healing | SYNEDGEN, INC. (US) | 2022-09-06 | — | — | US | disclosed |
| US-11077135-B2 | Derivatized chitosan polymers and methods of treating vascular disorders | SYNEDGEN, INC. (US) | 2021-08-03 | — | — | US | disclosed |
| US-11078154-B2 | Compositions and methods for the treatment of irritable bowel syndrome | CELLIX BIO PRIVATE LIMITED (IN) | 2021-08-03 | — | — | US | disclosed |
| US-10716803-B2 | Methods for treatment or prevention of damage resulting from radiation, trauma or shock | SYNEDGEN, INC. (US) | 2020-07-21 | — | — | US | disclosed |
| US-20200061192-A1 | DERIVATIZED POLYGLUCOSAMINES FOR DELIVERY OF SMALL MOLECULES, PEPTIDES, AND PROTEINS | SYNEDGEN INC (US) | 2020-02-27 | — | — | US | disclosed |
| WO-2019173602-A1 | 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2019-09-12 | — | — | WO | disclosed |
| US-8318323-B2 | Polycyclic compounds and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2012-11-27 | — | — | US | disclosed |
| US-8057919-B2 | Material for organic electroluminescence device and organic electroluminescence device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2011-11-15 | — | — | US | disclosed |
| US-8049411-B2 | Material for organic electroluminescence device and organic electroluminescence device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |
| WO-2011028968-A1 | ORAL CARE METHODS AND COMPOSITIONS UTILIZING CHITOSAN-DERIVATIVE COMPOUNDS | SYNEDGEN, INC. (US) | 2011-03-10 | — | — | WO | disclosed |
| WO-2011028967-A1 | METHODS AND COMPOSITIONS FOR DISRUPTING BIOFILM UTILIZING CHITOSAN-DERIVATIVE COMPOUNDS | SYNEDGEN INC. (US) | 2011-03-10 | — | — | WO | disclosed |
| US-20090309488-A1 | MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2009-12-17 | — | — | US | disclosed |
| US-20090302743-A1 | MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2009-12-10 | — | — | US | disclosed |
| EP-0688314-A1 | PRODRUG DERIVATIVES OF ENZYME INHIBITORS WITH HYDROXYL GROUPS, METHODS OF PREPARING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-12-27 | — | — | EP | disclosed |
| WO-1994021604-A1 | PRODRUG DERIVATIVES OF ENZYME INHIBITORS WITH HYDROXYL GROUPS, METHODS OF PREPARING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11433092-B2 | Compositions and methods of use for wound healing | PARG, ARGLU1, AREG | DPP7 599/4885GNAI3 1127/4885GNAO1 1350/4885 |
| US-20090302743-A1 | MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | ILK, EPCAM, PPOX | DPP7 4116/4885GNAI3 3935/4885GNAO1 1721/4885 |
| US-11078154-B2 | Compositions and methods for the treatment of irritable bowel syndrome | SI, SLC10A2, ALPI | DPP7 3926/4885GNAI3 873/4885GNAO1 1575/4885 |
| US-20090309488-A1 | MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | EPCAM, ILK, PPOX | DPP7 4262/4885GNAI3 3726/4885GNAO1 1801/4885 |
| US-10716803-B2 | Methods for treatment or prevention of damage resulting from radiation, trauma or shock | HMGB1, ELANE, SERPINB1 | DPP7 2861/4885GNAI3 2935/4885GNAO1 3235/4885 |
| US-20200061192-A1 | DERIVATIZED POLYGLUCOSAMINES FOR DELIVERY OF SMALL MOLECULES, PEPTIDES, AND PROTEINS | MUC1, DDOST, EPCAM | DPP7 330/4885GNAI3 638/4885GNAO1 1667/4885 |
| US-11717532-B2 | Methods and compositions for treating wounds utilizing chitosan compounds | CHIA, MMP8, CHIT1 | DPP7 550/4885GNAI3 3143/4885GNAO1 3506/4885 |
| US-11077135-B2 | Derivatized chitosan polymers and methods of treating vascular disorders | CHIA, CHI3L1, CHI3L2 | DPP7 765/4885GNAI3 3119/4885GNAO1 2677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.