Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | OTC | P00480 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.36 |
| ▸ | NPY4R | P50391 | 7/20 | 0.36 |
| ▸ | NPY1R | P25929 | 5/20 | 0.36 |
| ▸ | NPY2R | P49146 | 4/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30531668 | 0.88 | OTC (0.41) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL19465128 | 0.86 | DPP7 (0.39) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL2186467 | 0.86 | DPP7 (0.39) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL2186462 | 0.86 | DPP7 (0.39) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL5872015 | 0.85 | DPP7 (0.41) | DPP7OTCALOX15KMT2ADDAH1 | |
| SCHEMBL25302510 | 0.85 | OTC (0.39) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL21027152 | 0.84 | DPP7 (0.45) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL22799242 | 0.84 | NPY4R (0.38) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL22799243 | 0.84 | NPY4R (0.38) | DPP7OTCALOX15MEN1CYP1A2 | |
| SCHEMBL18819440 | 0.84 | DPP7 (0.45) | DPP7OTCALOX15MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2934565-A2 | GHRH AGONISTS FOR THE TREATMENT OF ISCHEMIC DISORDERS | University of Miami (US) | 2015-10-28 | — | — | EP | disclosed |
| WO-2014100809-A2 | GHRH AGONISTS FOR THE TREATMENT OF ISCHEMIC DISORDERS | UNIVERSITY OF MIAMI (US) | 2014-06-26 | — | — | WO | disclosed |
| US-7037897-B2 | TRI-, TETRA-, and penta-peptides having antiangiogenic activity | ABBOTT LABORATORIES (US) | 2006-05-02 | — | — | US | disclosed |
| US-7001984-B2 | Di-, tri-, and tetra-peptides having antiangiogenic activity | ABBOTT LABORATORIES (US) | 2006-02-21 | — | — | US | disclosed |
| US-20050215484-A1 | Di-, tri-, and tetra-peptides having antiangiogenic activity | HAVIV FORTUNA | 2005-09-29 | — | — | US | disclosed |