Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19249228 | 0.88 | PTPN5 (0.42) | PTPN5ALDH1A1L3MBTL1RAB9AMAPT | |
| SCHEMBL21865966 | 0.73 | PTPN5 (0.44) | PTPN5ALDH1A1L3MBTL1RAB9AMAPT | |
| SCHEMBL29545905 | 0.73 | ALDH1A1 (0.50) | PTPN5ALDH1A1L3MBTL1RAB9AMAPT | |
| SCHEMBL12329602 | 0.73 | ALDH1A1 (0.50) | PTPN5ALDH1A1L3MBTL1RAB9AMAPT | |
| SCHEMBL18664288 | 0.72 | CYP3A4 (0.38) | ALDH1A1MAPTKDM4EPKMHSD17B10 | |
| SCHEMBL13871750 | 0.72 | PTPN5 (0.47) | PTPN5ALDH1A1L3MBTL1RAB9AMAPT | |
| Ammonia Solution, Strong SCHEMBL27470283 | 0.71 | PTPN5 (0.42) | PTPN5ALDH1A1L3MBTL1RAB9AMAPT | |
| SCHEMBL26806644 | 0.71 | PTPN5 (0.42) | PTPN5ALDH1A1L3MBTL1RAB9AMAPT | |
| SCHEMBL9610071 | 0.69 | RAPGEF4 (0.42) | PTPN5ALDH1A1L3MBTL1RAB9AMAPT | |
| SCHEMBL18299676 | 0.69 | PTPN5 (0.41) | PTPN5ALDH1A1L3MBTL1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3636643-A1 | NUCLEAR RECEPTOR MODULATORS (ROR) FOR THE TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES | AbbVie Inc. (US) | 2020-04-15 | — | — | EP | disclosed |