SCHEMBL2186782

SCHEMBL2186782

C=CC(CC(=O)O)C(C=C)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.37
SLC22A6 Q4U2R8 1/20 0.35
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
BLM P54132 1/20 0.34
SLC6A3 Q01959 1/20 0.34
MEN1 O00255 1/20 0.34
CYP2D6 P10635 1/20 0.34
TSHR P16473 1/20 0.34
NFKB1 P19838 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 1/20 0.34
FOLH1 Q04609 2/20 0.32
HDAC2 Q92769 1/20 0.31
GABRR1 P24046 2/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11140563 0.83 SLC22A6 (0.43) TDP1SMN1; SMN2SLC22A6SLC6A2SLC6A4
SCHEMBL3751303 0.80 SLC6A2 (0.52) SLC6A2SLC6A4BLMSLC6A3MEN1
SCHEMBL8815410 0.77 TDP1 (0.56) TDP1SMN1; SMN2SLC22A6SLC6A2SLC6A4
SCHEMBL9802983 0.74 SLC22A6 (0.36) TDP1SMN1; SMN2SLC22A6SLC6A2SLC6A4
SCHEMBL28157180 0.74 LMNA (0.41) TDP1SLC6A2SLC6A4BLMSLC6A3
SCHEMBL7334419 0.73 SLC22A6 (0.40) TDP1SMN1; SMN2SLC22A6SLC6A2SLC6A4
SCHEMBL415931 0.70
SCHEMBL4406594 0.70
SCHEMBL3129296 0.70
SCHEMBL1201311 0.69 TDP1 (0.43) TDP1SMN1; SMN2SLC22A6SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110224374-A1 GLYOXALATED N-VINYLAMINE BASF SE (DE) 2011-09-15 US disclosed
EP-2343324-A1 Glyoxalated poly(n-vinylamine) BASF SE (DE) 2011-07-13 EP disclosed
US-5882841-A ULTRAHIGH CONTRAST, STORAGE STABILITY, UNIFORMITY, POLYMER PARTICLES CONTAINING A HYDRAZINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1999-03-16 US disclosed
EP-0317983-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1994-06-01 EP disclosed
US-5100771-A SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL WITH WATER INSOLUBLE ORGANIC SOLVENT SOLUBLE POLYMER FUJI PHOTO FILM CO., LTD. (JP) 1992-03-31 US disclosed
US-5047314-A Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-09-10 US disclosed
EP-0317983-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-05-31 EP disclosed