SCHEMBL21868232

SCHEMBL21868232

N=C(N)c1ccc2c(c1)sc1ccccc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.55
MAPT P10636 1/20 0.55
HPGD P15428 1/20 0.55
RAB9A P51151 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
GPR3 P46089 1/20 0.50
PLAU P00749 5/20 0.47
F2 P00734 4/20 0.47
PRSS1 P07477 3/20 0.47
PLG P00747 2/20 0.47
KLK1 P06870 2/20 0.47
KLKB1 P03952 1/20 0.47
F9 P00740 2/20 0.46
F10 P00742 2/20 0.46
NQO2 P16083 1/20 0.42
PLAT P00750 1/20 0.42
F12 P00748 1/20 0.42
F7 P08709 1/20 0.42
F3 P13726 1/20 0.42
PKM P14618 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL549174 0.91 PRSS1 (0.47) PLAUF2PRSS1PLGKLK1
Hydrochloric Acid SCHEMBL7054989 0.89 PRSS1 (0.45) PLAUF2PRSS1PLGKLK1
SCHEMBL25106253 0.82 ALDH1A1 (0.50) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL25894321 0.81 ALDH1A1 (0.49) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL21732405 0.80 ALDH1A1 (0.45) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL549114 0.79 PRSS1 (0.48) PLAUF2PRSS1PLGKLK1
SCHEMBL17117709 0.79 ALDH1A1 (0.44) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL25654653 0.78 ALDH1A1 (0.46) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL15041003 0.78 GPR3 (0.54) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2
SCHEMBL15040950 0.78 GPR3 (0.54) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020085740-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE USING SAME 주식회사 엘지화학 2020-04-30 WO disclosed
WO-2020067823-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 주식회사 엘지화학 2020-04-02 WO disclosed