SCHEMBL21868320

SCHEMBL21868320

CC1(C)c2ccccc2C2(c3ccccc3-c3c(-c4ccc5ccc6ccccc6c5n4)cccc32)c2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AR P10275 5/20 0.36
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
KDM4E B2RXH2 3/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
MAPT P10636 2/20 0.32
MAPK1 P28482 2/20 0.32
LMNA P02545 1/20 0.31
THRB P10828 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
RECQL P46063 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
TSHR P16473 1/20 0.30
MAPK3 P27361 1/20 0.30
PTPN11 Q06124 1/20 0.30
DHFR P00374 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24648293 0.92 AR (0.36) ARKDM4EALDH1A1HPGDMAPT
SCHEMBL21867873 0.81 PTGS2 (0.33) AR
SCHEMBL21867935 0.80 AR (0.33) ARMEN1KMT2AKDM4EALDH1A1
SCHEMBL24648077 0.79 ENPP1 (0.37) ARMEN1KMT2AKDM4EMAPT
SCHEMBL29444845 0.79 AR (0.35) ARMEN1KMT2AKDM4EALDH1A1
SCHEMBL20174714 0.79 MAPK1 (0.32) ARKMT2AKDM4EALDH1A1HPGD
SCHEMBL28343597 0.78 AR (0.38) ARMEN1KMT2AKDM4EALDH1A1
SCHEMBL21867566 0.76 BRD4 (0.40) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL21868024 0.75 RAB9A (0.41) ARMEN1KMT2AKDM4EALDH1A1
SCHEMBL25766691 0.75 KDM4E (0.39) ARMEN1KMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024114-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2023-01-26 US disclosed
US-20220376178-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2022-11-24 US disclosed
US-20220123218-A1 ORGANIC ELECTROLUMINESCENT DEVICE LG CHEM, LTD. (KR) 2022-04-21 US disclosed
WO-2020067823-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 주식회사 엘지화학 2020-04-02 WO disclosed