Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21869750 | 0.94 | KMT2A (0.67) | KMT2AGAAALDH1A1MAPTCYP3A4 | |
| SCHEMBL21869753 | 0.91 | KMT2A (0.63) | KMT2AGAAALDH1A1MAPTCYP3A4 | |
| SCHEMBL21869794 | 0.89 | HDAC1 (0.50) | KMT2AGAAHDAC1HDAC6 | |
| SCHEMBL28663232 | 0.89 | KMT2A (0.62) | KMT2AGAAALDH1A1MAPTCYP3A4 | |
| SCHEMBL21869747 | 0.89 | KMT2A (0.62) | KMT2AGAAALDH1A1MAPTCYP3A4 | |
| SCHEMBL21869798 | 0.89 | KMT2A (0.62) | KMT2AGAAALDH1A1MAPTCYP3A4 | |
| SCHEMBL21869752 | 0.89 | KMT2A (0.47) | KMT2AHDAC1HDAC6 | |
| SCHEMBL21869790 | 0.88 | GAA (0.62) | KMT2AGAAALDH1A1MAPTCYP3A4 | |
| SCHEMBL21869797 | 0.88 | GAA (0.49) | KMT2AGAAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL21869760 | 0.87 | KMT2A (0.60) | KMT2AGAAALDH1A1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109180552-B | Substituted 5-oxo pyrrolidine derivative and preparation method and application thereof | 沈阳药科大学 | 2021-10-26 | — | — | CN | disclosed |
| WO-2020063388-A1 | SUBSTITUTED 5-OXOPYRROLIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 沈阳药科大学 | 2020-04-02 | — | — | WO | disclosed |