Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PRKCA | P17252 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9863399 | 0.80 | ALDH1A1 (0.59) | ALDH1A1ADRB2ADRB1ADRB3POLB | |
| SCHEMBL16519863 | 0.79 | ADRB2 (0.57) | ALDH1A1ADRB2ADRB1ADRB3TDP1 | |
| SCHEMBL29964300 | 0.79 | ALDH1A1 (0.61) | ALDH1A1ADRB2ADRB1ADRB3POLB | |
| SCHEMBL3181495 | 0.79 | ALDH1A1 (0.61) | ALDH1A1ADRB2ADRB1ADRB3POLB | |
| SCHEMBL28686071 | 0.77 | ALDH1A1 (0.68) | ALDH1A1ADRB2ADRB1ADRB3PRKCA | |
| SCHEMBL28825260 | 0.77 | ALDH1A1 (0.79) | ALDH1A1ADRB2ADRB1ADRB3PRKCA | |
| SCHEMBL5153013 | 0.77 | ALDH1A1 (0.62) | ALDH1A1ADRB2ADRB1ADRB3PRKCA | |
| SCHEMBL10181432 | 0.77 | ADRB2 (0.48) | ALDH1A1ADRB2ADRB1ADRB3POLB | |
| SCHEMBL1926524 | 0.76 | ALDH1A1 (0.72) | ALDH1A1ADRB2ADRB1ADRB3PRKCA | |
| SCHEMBL27941692 | 0.76 | ALDH1A1 (0.67) | ALDH1A1ADRB2ADRB1ADRB3PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11129841-B2 | CD73 inhibitors | ORIC PHARMACEUTICALS, INC. (US) | 2021-09-28 | — | — | US | disclosed |
| US-20200093844-A1 | CD73 INHIBITORS | ORIC PHARMACEUTICALS, INC. | 2020-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11129841-B2 | CD73 inhibitors | ENTPD5, NT5E, ENTPD1 | ALDH1A1 889/4885ADRB2 3514/4885ADRB1 2864/4885 |
| US-20200093844-A1 | CD73 INHIBITORS | ENTPD5, NT5E, ENTPD1 | ALDH1A1 889/4885ADRB2 3514/4885ADRB1 2864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.