Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17824432 | 0.86 | CNR2 (0.35) | PTGS2S1PR1 | |
| SCHEMBL17824387 | 0.86 | S1PR1 (0.31) | S1PR1 | |
| SCHEMBL17832721 | 0.85 | PIK3CA (0.35) | S1PR1 | |
| SCHEMBL22190266 | 0.81 | KCNH2 (0.34) | S1PR1 | |
| SCHEMBL17832781 | 0.81 | CA12 (0.35) | PTGS2 | |
| SCHEMBL17824483 | 0.81 | KCNH2 (0.33) | PTGS2 | |
| SCHEMBL19684513 | 0.79 | LRRK2 (0.33) | S1PR1 | |
| SCHEMBL17824513 | 0.79 | CA12 (0.36) | PTGS2S1PR1 | |
| SCHEMBL19684781 | 0.79 | S1PR1 (0.32) | S1PR1 | |
| SCHEMBL17832777 | 0.79 | CA12 (0.34) | PTGS2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230284-B1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-04-15 | — | — | EP | disclosed |