Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24338016 | 0.80 | MAPT (0.59) | KMT2ANPC1LMNAMEN1HSD17B10 | |
| SCHEMBL4488799 | 0.80 | HSD17B10 (0.59) | KMT2ANPC1LMNAMEN1HSD17B10 | |
| SCHEMBL9314355 | 0.77 | KMT2A (0.66) | KMT2ANPC1LMNAMEN1HPGD | |
| SCHEMBL30114717 | 0.77 | HSD17B10 (0.59) | KMT2ANPC1LMNAMEN1HSD17B10 | |
| SCHEMBL21938140 | 0.77 | KMT2A (0.73) | KMT2ANPC1LMNAMEN1MAPT | |
| SCHEMBL3690385 | 0.77 | HPGD (0.77) | NPC1LMNAHSD17B10MAPTHPGD | |
| SCHEMBL31339222 | 0.76 | KMT2A (0.64) | KMT2ANPC1LMNAMEN1HPGD | |
| SCHEMBL9314349 | 0.76 | KMT2A (0.64) | KMT2ANPC1LMNAMEN1HPGD | |
| SCHEMBL28438962 | 0.76 | HPGD (0.57) | KMT2ANPC1LMNAMEN1HSD17B10 | |
| SCHEMBL6834014 | 0.75 | KMT2A (0.55) | KMT2ANPC1LMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3628374-B1 | BCL-3 INHIBITORS | UNIV COLLEGE CARDIFF CONSULTANTS LTD (GB) | 2023-08-30 | — | — | EP | disclosed |
| EP-3628374-A2 | BCL-3 INHIBITORS | University College Cardiff Consultants Limited (GB) | 2020-04-01 | — | — | EP | disclosed |