SCHEMBL3690385

SCHEMBL3690385

Cc1ccccc1NC(=O)c1ccccc1C

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.77
ALDH1A1 P00352 4/20 0.77
HTT P42858 3/20 0.77
HSD17B10 Q99714 3/20 0.77
LMNA P02545 2/20 0.77
KDM4E B2RXH2 1/20 0.77
MAPK1 P28482 1/20 0.77
POLB P06746 1/20 0.67
NPC1 O15118 2/20 0.64
RAB9A P51151 2/20 0.64
L3MBTL1 Q9Y468 3/20 0.64
MAPT P10636 2/20 0.62
CYP1A2 P05177 1/20 0.62
CYP2C9 P11712 1/20 0.62
CYP2C19 P33261 1/20 0.62
CSF1R P07333 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
KDM4C Q9H3R0 1/20 0.61
TP53 P04637 2/20 0.60
ATM Q13315 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30758600 0.87 HPGD (0.70) HPGDALDH1A1HTTHSD17B10LMNA
SCHEMBL11289021 0.87 HPGD (0.70) HPGDALDH1A1HTTHSD17B10LMNA
SCHEMBL11587152 0.87 HPGD (0.70) HPGDALDH1A1HTTHSD17B10LMNA
SCHEMBL28652342 0.87 HSD17B10 (0.70) HPGDALDH1A1HTTHSD17B10LMNA
SCHEMBL5079194 0.87 LMNA (1.00) HPGDALDH1A1HTTHSD17B10LMNA
SCHEMBL23367899 0.87 HPGD (0.61) HPGDALDH1A1HTTHSD17B10LMNA
SCHEMBL8252530 0.87 ALDH1A1 (0.72) HPGDALDH1A1HTTHSD17B10LMNA
SCHEMBL8812455 0.87 LMNA (0.75) HPGDALDH1A1HTTHSD17B10LMNA
SCHEMBL13164048 0.85 HPGD (0.74) HPGDALDH1A1HTTHSD17B10LMNA
SCHEMBL31462147 0.85 NPC1 (0.68) HPGDALDH1A1HTTHSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0620122-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1996-03-13 EP claimed
US-5446010-A Substrate sheet, thermosensitive colored image forming layer containing colorless dye precursor, binder, color developing agent having sulfonylureido group, aromatic amide sensitizer; storage stability NEW OJI PAPER CO., LTD. (JP) 1995-08-29 US claimed
EP-0620122-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-10-19 EP claimed
EP-3057618-B1 GLYCOENGINEERED ANTIBODY, ANTIBODY-CONJUGATE AND METHODS FOR THEIR PREPARATION SYNAFFIX BV (NL) 2022-12-14 EP disclosed
CN-109153684-B Electroactive compounds 株式会社LG化学 2021-12-21 CN disclosed
US-8647528-B2 Water absorbing agent and production method thereof NIPPON SHOKUBAI CO., LTD. (JP) 2014-02-11 US disclosed
US-20100270501-A1 Water absorbing agent and production method thereof NIPPON SHOKUBAI CO., LTD. (JP) 2010-10-28 US disclosed
US-20080167347-A1 Antidiabetic, antiproliferative, anticancer agents; benzanilide derivatives SHIONGI & CO., LTD. (JP) 2008-07-10 US disclosed
CN-1287046-C Method for producing paper and yield-improving agent SEIKO PMC CORP (JP) 2006-11-29 CN disclosed
CN-1643215-A Method for producing paper and yield-improving agent SEIKO PMC CORP (JP) 2005-07-20 CN disclosed
EP-0620122-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1996-03-13 EP disclosed
US-5446010-A Substrate sheet, thermosensitive colored image forming layer containing colorless dye precursor, binder, color developing agent having sulfonylureido group, aromatic amide sensitizer; storage stability NEW OJI PAPER CO., LTD. (JP) 1995-08-29 US disclosed
EP-0620122-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-10-19 EP disclosed
US-4123554-A Fungicidal and germicidal benzanilides KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1978-10-31 US disclosed
US-3985804-A Agricultural substituted 2-methylbenzanilide germicide KUMIAI CHEMICAL INDUSTRY CO., LTD. (JA) 1976-10-12 US disclosed
US-3937840-A COMPOSITIONS AND METHODS OF COMBATTING BACTERIA AND FUNGI USING 2-METHYLBENZANILIDE DERIVATIVES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JA) 1976-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080167347-A1 Antidiabetic, antiproliferative, anticancer agents; benzanilide derivatives CCNY, HDGF, GLI1 HPGD 2633/4885ALDH1A1 1472/4885HTT 1899/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.