Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.51 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814111 | 0.81 | SMN1; SMN2 (0.55) | KMT2ASORT1AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL6834682 | 0.77 | SORT1 (0.60) | KMT2ASORT1AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL355357 | 0.76 | ALDH1A1 (0.59) | KMT2ANPC1TDP1TP53L3MBTL1 | |
| SCHEMBL1307640 | 0.76 | ALDH1A1 (0.60) | KMT2ASORT1AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL6833870 | 0.75 | MAPT (0.63) | KMT2ASORT1AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL1308673 | 0.75 | AKR1C2 (0.62) | KMT2AAKR1C2AKR1C1AKR1C4AKR1C3 | |
| SCHEMBL6834021 | 0.75 | MAPT (0.54) | KMT2ASORT1AKR1C2AKR1C1AKR1C4 | |
| SCHEMBL21870545 | 0.75 | KMT2A (0.63) | KMT2ANPC1LMNATDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1375604 | 0.74 | ALDH1A1 (0.62) | KMT2ANPC1TDP1TP53L3MBTL1 | |
| SCHEMBL1310012 | 0.74 | AKR1C2 (0.60) | KMT2ASORT1AKR1C2AKR1C1AKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | KMT2A 2853/4885SORT1 2421/4885AKR1C2 2596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.