Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 5/20 | 0.35 |
| ▸ | CA2 | P00918 | 5/20 | 0.35 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.35 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.35 |
| ▸ | PTGIR | P43119 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6676349 | 0.77 | CACNA1C (0.48) | CACNA1CSCN5ASIGMAR1GRIN2DGRIN3B | |
| SCHEMBL21870800 | 0.72 | CCR2 (0.38) | CA1CA2MEN1KMT2ACCR2 | |
| SCHEMBL23962785 | 0.71 | HTR6 (0.46) | CA1CA2PSIP1CCR2HTR6 | |
| SCHEMBL23678601 | 0.70 | CCR2 (0.32) | CA1CA2CCR2JAK2JAK1 | |
| SCHEMBL20399181 | 0.67 | MEN1 (0.41) | CA1CA2MEN1KMT2ACA9 | |
| SCHEMBL6675317 | 0.67 | CACNA1C (0.49) | CACNA1CSCN5ASIGMAR1GRIN2DGRIN3B | |
| SCHEMBL6676424 | 0.66 | CACNA1C (0.48) | CACNA1CSCN5ASIGMAR1GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL6674250 | 0.66 | CACNA1C (0.48) | CACNA1CSCN5ASIGMAR1GRIN2DGRIN3B | |
| SCHEMBL28340525 | 0.66 | CA1 (0.39) | CA1CA2MEN1KMT2ACA9 | |
| Hydrochloric Acid SCHEMBL6675369 | 0.65 | CACNA1C (0.47) | CACNA1CSCN5ASIGMAR1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020057669-A1 | AROMATIC HETEROCYCLIC COMPOUND WITH KINASE INHIBITORY ACTIVITY | 上海轶诺药业有限公司 | 2020-03-26 | — | — | WO | disclosed |