Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 2/20 | 0.43 |
| ▸ | ACLY | P53396 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5164813 | 0.83 | PTPN1 (0.53) | PTPN1STAT3ACLYALDH1A1TAS2R14 | |
| SCHEMBL5164817 | 0.82 | PTPN1 (0.42) | PTPN1STAT3ACLYALDH1A1TAS2R14 | |
| SCHEMBL5163348 | 0.79 | PTPN1 (0.47) | PTPN1STAT3ACLYALDH1A1TAS2R14 | |
| SCHEMBL5163343 | 0.78 | PTPN1 (0.67) | PTPN1STAT3ALDH1A1 | |
| SCHEMBL5166571 | 0.77 | PTPN1 (0.47) | PTPN1ALDH1A1TAS2R14LMNAMAPT | |
| SCHEMBL5166577 | 0.77 | ALDH1A1 (0.41) | PTPN1ACLYALDH1A1TAS2R14LMNA | |
| SCHEMBL5164531 | 0.74 | NR1H2 (0.40) | ACLYALDH1A1TAS2R14LMNAMAPT | |
| SCHEMBL5164528 | 0.73 | PTPN1 (0.45) | PTPN1ALDH1A1TAS2R14LMNAMAPT | |
| SCHEMBL5163073 | 0.72 | PTPN1 (0.45) | PTPN1ALDH1A1LMNAMAPTHTT | |
| SCHEMBL5163077 | 0.71 | LMNA (0.40) | PTPN1ACLYALDH1A1TAS2R14LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200115357-A1 | LIVER X RECEPTORS (LXR) MODULATORS | PHENEX-FXR GMBH (DE) | 2020-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200115357-A1 | LIVER X RECEPTORS (LXR) MODULATORS | NR1H2, NR1H3, NR1H4 | PTPN1 989/4885CA12 4480/4885CA1 4295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.