⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21872420 | 0.84 | — | — | |
| SCHEMBL21872491 | 0.82 | IL1B (0.34) | — | |
| SCHEMBL24900934 | 0.77 | — | — | |
| SCHEMBL21872459 | 0.77 | — | — | |
| SCHEMBL21872399 | 0.71 | — | — | |
| SCHEMBL21872448 | 0.70 | — | — | |
| SCHEMBL21936271 | 0.69 | — | — | |
| SCHEMBL27169591 | 0.66 | LMNA (0.39) | — | |
| SCHEMBL21872871 | 0.61 | — | — | |
| SCHEMBL21872860 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632897-A1 | NOVEL BIPHENYL COMPOUND OR SALT THEREOF | Taiho Pharmaceutical Co., Ltd. (JP) | 2020-04-08 | — | — | EP | disclosed |
| EP-3633380-A1 | METHOD FOR PREDICTING THERAPEUTIC EFFECT OF LSD1 INHIBITOR BASED ON EXPRESSION OF INSM1 | Taiho Pharmaceutical Co., Ltd. (JP) | 2020-04-08 | — | — | EP | disclosed |