Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 2/20 | 0.39 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.38 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9384038 | 0.85 | KMT2A (0.55) | KMT2ARAB9AKDM4ENPC1ALDH1A1 | |
| SCHEMBL10277534 | 0.82 | KMT2A (0.52) | KMT2ARAB9AKDM4ENPC1ALDH1A1 | |
| SCHEMBL11123118 | 0.80 | KMT2A (0.59) | KMT2ARAB9AKDM4ENPC1ALDH1A1 | |
| SCHEMBL17206355 | 0.80 | KMT2A (0.53) | KMT2ARAB9AKDM4ENPC1ALDH1A1 | |
| SCHEMBL13792157 | 0.80 | KMT2A (0.53) | KMT2ARAB9AKDM4ENPC1ALDH1A1 | |
| SCHEMBL5206196 | 0.79 | KMT2A (0.48) | KMT2ARAB9AKDM4ENPC1ALDH1A1 | |
| SCHEMBL7494123 | 0.78 | RAB9A (0.68) | KMT2ARAB9AKDM4ENPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2188431 | 0.78 | KMT2A (0.52) | KMT2ARAB9AKDM4ENPC1ALDH1A1 | |
| Methane SCHEMBL11623540 | 0.78 | KMT2A (0.47) | KMT2ARAB9AKDM4ENPC1ALDH1A1 | |
| SCHEMBL15338801 | 0.77 | KMT2A (0.60) | KMT2ARAB9AKDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993775-B2 | Chromium and nickel catalysts for oligomerization reactions and process for obtaining alpha-olefins using said catalysts | Petroleo Brasileiro S.A.—Petrobras (BR) | 2015-03-31 | — | — | US | disclosed |
| US-20120178939-A1 | Chromium and nickel catalysts for oligomerization recations and process for obtaining alpha-olefins using said catalysts | UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL - UFRGS (BR) | 2012-07-12 | — | — | US | disclosed |
| CN-101538243-B | Malononitrile compounds and their use | SUMITOMO CHEMICAL CO | 2012-05-09 | — | — | CN | disclosed |
| CN-101544606-B | Malononitrile compound and use thereof | SUMITOMO CHEMICAL CO | 2012-02-29 | — | — | CN | disclosed |
| EP-1710234-B1 | MALONONITRILE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2011-07-13 | — | — | EP | disclosed |
| EP-1710234-B1 | MALONONITRILE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2011-07-13 | — | — | EP | disclosed |
| CN-1910147-B | Malononitrile compounds and their use | SUMITOMO CHEMICAL CO | 2011-04-20 | — | — | CN | disclosed |
| CN-101544606-A | Malononitrile compound and use thereof | SUMITOMO CHEMICAL CO | 2009-09-30 | — | — | CN | disclosed |
| CN-101538243-A | Malononitrile compound and use thereof | SUMITOMO CHEMICAL CO | 2009-09-23 | — | — | CN | disclosed |
| US-7541374-B2 | Malononitrile compounds and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-02 | — | — | US | disclosed |
| US-7541374-B2 | Malononitrile compounds and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-02 | — | — | US | disclosed |
| US-7541374-B2 | Malononitrile compounds and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-02 | — | — | US | disclosed |
| US-20070117854-A1 | Malononitrile compounds and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-24 | — | — | US | disclosed |
| US-20070117854-A1 | Malononitrile compounds and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-24 | — | — | US | disclosed |
| US-20070117854-A1 | Malononitrile compounds and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-24 | — | — | US | disclosed |
| CN-1910147-A | Malononitrile compounds and their use | SUMITOMO CHEMICAL CO (JP) | 2007-02-07 | — | — | CN | disclosed |
| EP-1710234-A1 | MALONONITRILE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2006-10-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178939-A1 | Chromium and nickel catalysts for oligomerization recations and process for obtaining alpha-olefins using said catalysts | PCNA, ORC3, AOC3 | KMT2A 4545/4885RAB9A 3628/4885KDM4E 4417/4885 |
| US-20070117854-A1 | Malononitrile compounds and use thereof | ME1, DDT, CYP51A1 | KMT2A 2412/4885RAB9A 1607/4885KDM4E 1179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.