SCHEMBL21873268

SCHEMBL21873268

CCSc1nc(-c2ccccc2O)nc(-c2cc3ccccc3c3ccccc23)n1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 2/20 0.52
▸ TDP1 Q9NUW8 2/20 0.44
▸ USP2 O75604 1/20 0.44
▸ MAPT P10636 8/20 0.43
▸ KMT2A Q03164 6/20 0.43
▸ TSHR P16473 5/20 0.43
▸ MEN1 O00255 4/20 0.43
▸ POLB P06746 2/20 0.43
▸ HPGD P15428 2/20 0.43
▸ LMNA P02545 4/20 0.42
▸ ALDH1A1 P00352 3/20 0.42
▸ HTT P42858 2/20 0.42
▸ ATM Q13315 2/20 0.42
▸ NPSR1 Q6W5P4 3/20 0.40
▸ NPC1 O15118 1/20 0.40
▸ RXFP1 Q9HBX9 1/20 0.40
▸ TRPM4 Q8TD43 1/20 0.39
▸ L3MBTL1 Q9Y468 2/20 0.39
▸ ALOX15 P16050 2/20 0.39
▸ KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21873275 0.91 MAPK1 (0.49) MAPK1TDP1USP2MAPTKMT2A
SCHEMBL24431772 0.90 MAPK1 (0.50) MAPK1TDP1USP2MAPTKMT2A
SCHEMBL24431972 0.86 MAPK1 (0.46) MAPK1TDP1USP2MAPTKMT2A
SCHEMBL21873277 0.85 MAPK1 (0.74) MAPK1TDP1USP2MAPTKMT2A
SCHEMBL24431976 0.83 MAPK1 (0.41) MAPK1TDP1USP2MAPTKMT2A
SCHEMBL24431818 0.82 MAPK1 (0.47) MAPK1TDP1USP2MAPTKMT2A
SCHEMBL21872923 0.82 MAPK1 (0.52) MAPK1TDP1USP2MAPTKMT2A
SCHEMBL21873776 0.80 MAPK1 (0.33) MAPK1TDP1USP2MAPTKMT2A
SCHEMBL24431662 0.79 MAPT (0.55) MAPK1TDP1MAPTKMT2ATSHR
SCHEMBL21873271 0.79 MAPK1 (0.49) MAPK1TDP1USP2MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220158099-A1 DISPLAY APPARATUS AND LIGHT ABSORBER INCLUDED IN DISPLAY APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2022-05-19 — — US disclosed
WO-2020071695-A1 DISPLAY APPARATUS AND LIGHT ABSORBER INCLUDED IN DISPLAY APPARATUS 삼성디스플레이 주식회사 2020-04-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220158099-A1 DISPLAY APPARATUS AND LIGHT ABSORBER INCLUDED IN DISPLAY APPARATUS CRY1, EPHB4, HTR3D MAPK1 4734/4885TDP1 4546/4885USP2 1773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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