SCHEMBL21873277

SCHEMBL21873277

CSc1nc(-c2ccccc2O)nc(-c2cc3ccccc3c3ccccc23)n1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 2/20 0.74
▸ KMT2A Q03164 7/20 0.42
▸ TRPM4 Q8TD43 1/20 0.42
▸ SMN1; SMN2 Q16637 2/20 0.41
▸ HSP90AA1 P07900 2/20 0.41
▸ MAPT P10636 7/20 0.40
▸ TSHR P16473 5/20 0.40
▸ MEN1 O00255 5/20 0.40
▸ ALDH1A1 P00352 3/20 0.40
▸ HPGD P15428 3/20 0.40
▸ ALOX15 P16050 2/20 0.40
▸ POLB P06746 1/20 0.40
▸ ADORA3 P0DMS8 1/20 0.40
▸ ADORA2A P29274 1/20 0.40
▸ ADORA2B P29275 1/20 0.40
▸ ADORA1 P30542 1/20 0.40
▸ NPSR1 Q6W5P4 4/20 0.39
▸ KDM4E B2RXH2 2/20 0.39
▸ LMNA P02545 2/20 0.39
▸ NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21873276 0.91 MAPK1 (0.68) MAPK1KMT2ASMN1; SMN2HSP90AA1MAPT
SCHEMBL21872923 0.85 MAPK1 (0.52) MAPK1KMT2ATRPM4SMN1; SMN2MAPT
SCHEMBL21873268 0.85 MAPK1 (0.52) MAPK1KMT2ATRPM4SMN1; SMN2MAPT
SCHEMBL21873281 0.84 MAPK1 (0.52) MAPK1KMT2ASMN1; SMN2MAPTMEN1
SCHEMBL24431772 0.83 MAPK1 (0.50) MAPK1KMT2ATRPM4SMN1; SMN2MAPT
SCHEMBL24431561 0.80 KMT2A (0.47) MAPK1KMT2ATRPM4SMN1; SMN2MAPT
SCHEMBL24431972 0.79 MAPK1 (0.46) MAPK1KMT2AMAPTTSHRMEN1
SCHEMBL24431662 0.77 MAPT (0.55) MAPK1KMT2ATRPM4SMN1; SMN2MAPT
SCHEMBL24431810 0.77 MAPT (0.55) MAPK1KMT2ATRPM4SMN1; SMN2MAPT
SCHEMBL21873280 0.77 MAPK1 (0.68) MAPK1KMT2ASMN1; SMN2HSP90AA1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220158099-A1 DISPLAY APPARATUS AND LIGHT ABSORBER INCLUDED IN DISPLAY APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2022-05-19 — — US disclosed
WO-2020071695-A1 DISPLAY APPARATUS AND LIGHT ABSORBER INCLUDED IN DISPLAY APPARATUS 삼성디스플레이 주식회사 2020-04-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220158099-A1 DISPLAY APPARATUS AND LIGHT ABSORBER INCLUDED IN DISPLAY APPARATUS CRY1, EPHB4, HTR3D MAPK1 4734/4885KMT2A 2009/4885TRPM4 729/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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