SCHEMBL2187366

SCHEMBL2187366

[CH2]C(=C)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL60364 0.70
SCHEMBL20591244 0.70
SCHEMBL5674597 0.70
SCHEMBL776535 0.70
SCHEMBL26574 0.70
SCHEMBL2669795 0.70
SCHEMBL9455389 0.70
SCHEMBL24353240 0.67
SCHEMBL3421463 0.67
SCHEMBL347823 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1152679-C Melatonergic agents of benzodioxoles, benzofurans, dihydrobenzofurans and benzodioxanes ����˹�ж�-����˹˹������˾ 2004-06-09 CN claimed
CN-1239886-A Benzodioxole, benzofuran, dihydrobenzofuran, and benzodioxane melatonergic agent BRISTOL MYERS SQUIBB CO (US) 1999-12-29 CN claimed
US-11993578-B2 Pyrazole-3-carboxylic acid amide derivative and pest control agent KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-05-28 US disclosed
US-11964957-B2 Pyrazole derivative and harmful organism-controlling agent KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-04-23 US disclosed
EP-3808738-B1 PYRAZOLE DERIVATIVE AND HARMFUL ORGANISM-CONTROLLING AGENT KUMIAI CHEMICAL INDUSTRY CO (JP) 2024-04-17 EP disclosed
EP-4317160-A1 HETEROCYCLIC COMPOUND AND USE THEREOF Kumiai Chemical Industry Co., Ltd. (JP) 2024-02-07 EP disclosed
CN-117098759-A Heterocyclic compounds and their use 组合化学工业株式会社 2023-11-21 CN disclosed
CN-110612295-B Pyrazole-3-carboxylic acid amide derivative and pest control agent 组合化学工业株式会社 2023-07-14 CN disclosed
US-20230110603-A1 3-ALKOXYBENZAMIDE DERIVATIVE, AND PEST CONTROL AGENT KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2023-04-13 US disclosed
EP-3623365-B1 PYRAZOLE-3-CARBOXYLIC ACID AMIDE DERIVATIVE AND PEST CONTROL AGENT KUMIAI CHEMICAL INDUSTRY CO (JP) 2023-01-04 EP disclosed
EP-4098650-A1 3-ALKOXY BENZOIC ACID AMIDE DERIVATIVE, AND PEST CONTROL AGENT Kumiai Chemical Industry Co., Ltd. (JP) 2022-12-07 EP disclosed
US-5238523-A Apparatus for producing a liquid crystal optical device IDEMITSU KOSAN CO., LTD. (JP) 1993-08-24 US disclosed
US-5231525-A Apparatus for orienting a liquid crystal material using a shear force and electric field IDEMITSU KOSAN CO., LTD. (JP) 1993-07-27 US disclosed
EP-0514540-A1 PYRROLO 2,3-d]PYRIMIDINE DERIVATIVE, PROCESS FOR PREPARING THE SAME, AND PHARMACEUTICAL PREPARATION COMPRISING THE DERIVATIVE AS ACTIVE INGREDIENT TEIJIN LIMITED (JP) 1992-11-25 EP disclosed
US-5145546-A Method of producing a substrate coated with a film of liquid crystal material and method of producing a liquid crystal optical device IDEMITSU KOSAN CO., LTD. (JP) 1992-09-08 US disclosed
EP-0495982-A1 BICYCLIC PYRIMIDINE DERIVATIVE, METHOD OF PRODUCING THE SAME, AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME AS ACTIVE INGREDIENT TEIJIN LIMITED (JP) 1992-07-29 EP disclosed
US-5110623-A Shearing while applying electric field IDEMITSU KOSAN CO., LTD. (JP) 1992-05-05 US disclosed
EP-0400654-A2 Method of orienting a liquid crystal material, apparatus therefor, and liquid crystal device oriented thereby IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-12-05 EP disclosed
US-4094833-A Vinylic group containing dextran derivative gel in particle form for separation purposes PHARMACIA FINE CHEMICALS AB (SW) 1978-06-13 US disclosed
US-4094832-A Vinylic group containing dextran derivative gel for use in electrophoretic separation processes PHARMACIA FINE CHEMICALS AB (SW) 1978-06-13 US disclosed