Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21874522 | 0.85 | ALDH1A1 (0.45) | LMNAMAPK1KMT2AKDM4EMAPT | |
| SCHEMBL31490811 | 0.85 | ALDH1A1 (0.45) | LMNAMAPK1KMT2AKDM4EMAPT | |
| SCHEMBL17204739 | 0.84 | LMNA (0.44) | LMNAMAPK1KMT2AKDM4EMAPT | |
| SCHEMBL21874471 | 0.82 | KDM4E (0.60) | LMNAMAPK1KMT2AKDM4EMAPT | |
| SCHEMBL21874462 | 0.82 | LMNA (0.43) | LMNAMAPK1KMT2AKDM4EMAPT | |
| SCHEMBL21874508 | 0.81 | MCL1 (0.56) | MAPK1HDAC1HDAC8HDAC6 | |
| SCHEMBL21950022 | 0.77 | HDAC1 (0.33) | ALDH1A1HDAC1HDAC8HDAC6CASP3 | |
| SCHEMBL31370875 | 0.77 | PFKFB3 (0.46) | LMNAMAPK1KMT2AKDM4EMAPT | |
| SCHEMBL4386528 | 0.75 | LMNA (0.69) | LMNAMAPK1KMT2AKDM4EMAPT | |
| SCHEMBL9920686 | 0.75 | MAPT (0.44) | COMTLMNAMAPK1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12435068-B2 | Anthelmintic compounds | ELANCO ANIMAL HEALTH GMBH (DE) | 2025-10-07 | — | — | US | disclosed |
| CN-119409690-A | Novel insect repellent compound | 拜耳动物保健有限责任公司 | 2025-02-11 | — | — | CN | disclosed |
| US-20210380566-A1 | NEW ANTHELMINTIC COMPOUNDS | ELANCO ANIMAL HEALTH GMBH (DE) | 2021-12-09 | — | — | US | disclosed |
| US-20210380566-A1 | NEW ANTHELMINTIC COMPOUNDS | ELANCO ANIMAL HEALTH GMBH (DE) | 2021-12-09 | — | — | US | disclosed |
| CN-113166123-A | Novel insect repellent compounds | 拜耳动物保健有限责任公司 | 2021-07-23 | — | — | CN | disclosed |
| EP-3847168-A2 | NEW ANTHELMINTIC COMPOUNDS | Bayer Animal Health GmbH (DE) | 2021-07-14 | — | — | EP | disclosed |
| EP-3643711-A1 | NEW ANTHELMINTIC COMPOUNDS | Bayer Animal Health GmbH (DE) | 2020-04-29 | — | — | EP | disclosed |
| EP-3643711-A1 | NEW ANTHELMINTIC COMPOUNDS | Bayer Animal Health GmbH (DE) | 2020-04-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12435068-B2 | Anthelmintic compounds | H1-10, HRH2, HRH1 | COMT 3392/4885LMNA 1634/4885MAPK1 3727/4885 |
| US-20210380566-A1 | NEW ANTHELMINTIC COMPOUNDS | H1-10, HRH2, HRH4 | COMT 3570/4885LMNA 1689/4885MAPK1 3604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.