SCHEMBL21879710

SCHEMBL21879710

[c]1cc(-c2cccnc2)c2sc3ccccc3c2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 2/20 0.44
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
CYP2A6 P11509 7/20 0.40
ALOX5 P09917 2/20 0.40
CYP3A4 P08684 3/20 0.39
ALDH1A1 P00352 2/20 0.39
CYP1A2 P05177 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
HIF1A Q16665 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
NUDT1 P36639 1/20 0.38
CYP2E1 P05181 2/20 0.38
CYP2D6 P10635 2/20 0.38
CYP2C9 P11712 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28570273 0.84 GPR3 (0.39) NPC1RAB9AALOX5ALDH1A1CYP1A2
SCHEMBL21295648 0.83 GPR3 (0.45) RAB9AALOX5ALDH1A1KDM4EMEN1
SCHEMBL21295631 0.82 CYP11B1 (0.43) CYP11B1NPC1RAB9ACYP2A6ALOX5
SCHEMBL21296044 0.80 ALOX5 (0.40) CYP11B1NPC1RAB9ACYP2A6ALOX5
SCHEMBL21296065 0.77 ALOX5 (0.40) CYP11B1NPC1RAB9ACYP2A6ALOX5
SCHEMBL28583779 0.75 MIF (0.44) NPC1RAB9AALOX5ALDH1A1CYP1A2
SCHEMBL21295816 0.75 CYP11B1 (0.42) CYP11B1NPC1RAB9ACYP2A6ALOX5
SCHEMBL23372685 0.75 MEN1 (0.47) CYP11B1NPC1RAB9ACYP2A6ALOX5
SCHEMBL21295945 0.73 NPC1 (0.41) CYP11B1NPC1RAB9ACYP2A6ALOX5
SCHEMBL14725756 0.73 CYP11B1 (0.50) CYP11B1NPC1RAB9ACYP2A6ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed
WO-2020085319-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2020-04-30 WO disclosed