Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2268057 | 0.97 | PNMT (0.35) | PNMTNPC1RAB9ADRD2DRD4 | |
| Fluoride Ion SCHEMBL1131088 | 0.97 | PNMT (0.35) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL218578 | 0.88 | PNMT (0.34) | PNMTNPC1RAB9ADRD2DRD4 | |
| Fluoride Ion SCHEMBL1130850 | 0.85 | PNMT (0.34) | PNMTNPC1RAB9APGR | |
| Hydrochloric Acid SCHEMBL5351419 | 0.85 | PNMT (0.44) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL7185528 | 0.84 | PNMT (0.39) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL813119 | 0.83 | PNMT (0.34) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL814376 | 0.83 | PNMT (0.31) | PNMTNPC1RAB9A | |
| Fluoride Ion SCHEMBL1130432 | 0.82 | PNMT (0.44) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL217903 | 0.82 | PNMT (0.37) | PNMTNPC1RAB9ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9394388-B2 | Hybrid supported metallocene catalyst, method for preparing the same, and process for preparing polyolefin using the same | SK INNOVATION CO., LTD. (KR) | 2016-07-19 | — | — | US | claimed |
| US-20150025204-A1 | Hybrid Supported Metallocene Catalyst, Method for Preparing the Same, and Process for Preparing Polyolefin Using the Same | SK INNOVATION CO., LTD. (KR) | 2015-01-22 | — | — | US | claimed |
| WO-2013133595-A1 | HYBRID SUPPORTED METALLOCENE CATALYST, METHOD FOR PREPARING THE SAME, AND PROCESS FOR PREPARING POLYOLEFIN USING THE SAME | SK INNOVATION CO., LTD. (KR) | 2013-09-12 | — | — | WO | claimed |
| US-7662895-B2 | comprising polypropylene which is produced in presence of a metallocene transition metal catalyst and an activator; peak melting point temperature below about 110 degrees C., a tensile set of 40% or less, and greater than or equal to about 60% [r]dyads | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-02-16 | — | — | US | claimed |
| US-20070117941-A1 | Syndiotactic propylene elastomers | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-05-24 | — | — | US | claimed |
| US-7101939-B2 | Ethylene/α-olefin copolymer made with a non-single-site/single-site catalyst combination, its preparation and use | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-09-05 | — | — | US | claimed |
| US-20050054791-A1 | low density, high impact strength, high tear resistance and high clarity, a degree of stiffness usually found in products made from resin of significantly higher density | EXXONMOBIL CHEMICAL PATENTS INC. | 2005-03-10 | — | — | US | claimed |
| EP-1461364-A1 | ETHYLENE/ALPHA-OLEFIN COPOLYMER MADE WITH A NON-SINGLE-SITE/SINGLE-SITE CATALYST COMBINATION, ITS PREPARATION AND USE | Exxonmobil Chemical Patents Inc. (US) | 2004-09-29 | — | — | EP | claimed |
| WO-2003048213-A1 | ETHYLENE/ALPHA-OLEFIN COPOLYMER MADE WITH A NON-SINGLE-SITE/SINGLE-SITE CATALYST COMBINATION, ITS PREPARATION AND USE | EXXONMOBIL CHEMICAL PATENTS, INC. (US) | 2003-06-12 | — | — | WO | claimed |
| CN-117736358-A | Metallocene polyethylene for sintering and preparation method and application thereof | 上海化工研究院有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-109666090-B | Supported metallocene catalyst for olefin polymerization reaction, preparation method and application | 中国石油化工股份有限公司 | 2021-09-21 | — | — | CN | disclosed |
| EP-2050771-B1 | FILM OR LAMINATE COMPRISING ETHYLENE RESIN OR ETHYLENE RESIN COMPOSITION | MITSUI CHEMICALS INC (JP) | 2020-07-15 | — | — | EP | disclosed |
| US-10457786-B2 | Biaxially-stretched film and ethylene polymer composition | PRIME POLYMER CO., LTD. (JP) | 2019-10-29 | — | — | US | disclosed |
| CN-109666090-A | A kind of load metallocene catalyst for olefin polymerization, preparation method and application | 中国石油化工股份有限公司 | 2019-04-23 | — | — | CN | disclosed |
| EP-1025137-B1 | PHOTO-POLYMERIZATION OF VINYL CHLORIDE USING METALLOCENE CATALYSTS | OXY VINYLS LP (US) | 2001-09-26 | — | — | EP | disclosed |
| EP-1022292-A2 | Ethylene-1-butene random copolymer and polypropylene resin composition comprising the same | JSR Corporation (JP) | 2000-07-26 | — | — | EP | disclosed |
| US-5914372-A | VULCANIZABLE RUBBER CONSISTS OF A COPOLYMER OF ETHYLENE-ALPHA-OLEFIN-NON-CONJUGATED DIENE, ATLEAST ONE VULCANIZING AGENT, AND A PEROXY CROOSLINKING AGENT | JSR CORPORATION (JP) | 1999-06-22 | — | — | US | disclosed |
| EP-0855413-A1 | Ethylene copolymer rubber composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |
| EP-0748825-A2 | Ethylene-alpha-olefin-non-conjugated diene copolymer rubber | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1996-12-18 | — | — | EP | disclosed |
| US-5401817-A | Syndiotactic polypropylene | PHILLIPS PETROLEUM COMPANY (US) | 1995-03-28 | — | — | US | disclosed |