Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.56 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | PTPRC | P08575 | 3/20 | 0.53 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13849150 | 0.86 | TTR (0.63) | L3MBTL1ATMTDP1ALDH1A1SRD5A2 | |
| SCHEMBL17196578 | 0.82 | PTPRC (0.61) | L3MBTL1ATMTDP1ALDH1A1SRD5A2 | |
| SCHEMBL11814593 | 0.82 | PTPRC (0.61) | L3MBTL1ATMTDP1ALDH1A1SRD5A2 | |
| SCHEMBL6421185 | 0.82 | ATM (0.59) | L3MBTL1ATMTDP1ALDH1A1SRD5A2 | |
| SCHEMBL27560697 | 0.80 | TTR (0.72) | L3MBTL1ATMTDP1ALDH1A1SRD5A2 | |
| SCHEMBL314267 | 0.79 | ALDH1A1 (0.93) | L3MBTL1ATMTDP1ALDH1A1SRD5A2 | |
| SCHEMBL9066312 | 0.79 | ALDH1A1 (0.93) | L3MBTL1ATMTDP1ALDH1A1SRD5A2 | |
| SCHEMBL1271059 | 0.79 | TDP1 (0.55) | L3MBTL1ATMTDP1ALDH1A1SRD5A2 | |
| SCHEMBL11422252 | 0.77 | ATM (0.53) | L3MBTL1ATMTDP1ALDH1A1SRD5A2 | |
| SCHEMBL9324919 | 0.77 | ATM (1.00) | L3MBTL1ATMTDP1ALDH1A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342172-B1 | BIFLUORENYLIDENE DERIVATIVES, THEIR PREPARATION AND USES THEREOF | UNIV ROMA (IT) | 2012-08-08 | — | — | EP | disclosed |
| EP-2342172-B1 | BIFLUORENYLIDENE DERIVATIVES, THEIR PREPARATION AND USES THEREOF | UNIV ROMA (IT) | 2012-08-08 | — | — | EP | disclosed |
| EP-2342172-A1 | BIFLUORENYLIDENE DERIVATIVES, THEIR PREPARATION AND USES THEREOF | Università degli Studi di Roma "La Sapienza" (IT) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010038251-A1 | BIFLUORENYLIDENE DERIVATIVES, THEIR PREPARATION AND USES THEREOF | UNIVERSITÀ DEGLI STUDI DI ROMA LA SAPIENZA (IT) | 2010-04-08 | — | — | WO | disclosed |
| WO-2010038251-A1 | BIFLUORENYLIDENE DERIVATIVES, THEIR PREPARATION AND USES THEREOF | UNIVERSITÀ DEGLI STUDI DI ROMA LA SAPIENZA (IT) | 2010-04-08 | — | — | WO | disclosed |