SCHEMBL21881741

SCHEMBL21881741

CC(C)COC(=O)CC[C@H](NC(=O)n1ccnc1)C(=O)OCC(C)C

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP26A1 O43174 5/20 0.43
CYP3A4 P08684 3/20 0.39
CYP2C19 P33261 3/20 0.39
CYP1A2 P05177 2/20 0.39
CYP2D6 P10635 2/20 0.39
CYP2C9 P11712 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.37
KMT2A Q03164 2/20 0.36
POLB P06746 2/20 0.36
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TLR2 O60603 1/20 0.31
GAA P10253 1/20 0.31
TBXAS1 P24557 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4674105 0.79 P2RY12 (0.35) L3MBTL1KMT2APOLBGAA
SCHEMBL4671255 0.79 P2RY12 (0.35) L3MBTL1KMT2APOLBGAA
SCHEMBL4671250 0.79 P2RY12 (0.35) L3MBTL1KMT2APOLBGAA
SCHEMBL22365090 0.77 P2RY12 (0.33) CYP2C19CYP1A2CYP2C9L3MBTL1KMT2A
SCHEMBL10402927 0.75 CYP26A1 (0.40) CYP26A1CYP3A4CYP2D6KMT2AALDH1A1
SCHEMBL23067830 0.74 P2RY12 (0.38) L3MBTL1
SCHEMBL23067828 0.74 TBXAS1 (0.38) CYP26A1KMT2ATBXAS1
SCHEMBL29100674 0.73 HRH4 (0.49) KMT2AALDH1A1HPGD
SCHEMBL29100675 0.73 HRH4 (0.49) KMT2AALDH1A1HPGD
SCHEMBL22365088 0.72 P2RY12 (0.34) L3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230382918-A1 RADIOPHARMACEUTICALS, RADIOIMAGING AGENTS, AND USES THEREOF Clarity Pharmaceuticals Ltd (AU) 2023-11-30 US disclosed
US-11384088-B2 Radiopharmaceuticals, radioimaging agents, and uses thereof Clarity Pharmaceuticals Ltd (AU) 2022-07-12 US disclosed
US-10975089-B2 Radiopharmaceuticals, radioimaging agents, and uses thereof Clarity Pharmaceuticals Ltd (AU) 2021-04-13 US disclosed
US-20200095257-A1 RADIOPHARMACEUTICALS, RADIOIMAGING AGENTS, AND USES THEREOF THE UNIVERSITY OF MELBOURNE (AU) 2020-03-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11384088-B2 Radiopharmaceuticals, radioimaging agents, and uses thereof SLC30A5, SLC40A1, FOLH1 CYP26A1 3944/4885CYP3A4 4624/4885CYP2C19 4504/4885
US-20230382918-A1 RADIOPHARMACEUTICALS, RADIOIMAGING AGENTS, AND USES THEREOF SLC30A5, SLC40A1, FOLH1 CYP26A1 3944/4885CYP3A4 4624/4885CYP2C19 4504/4885
US-10975089-B2 Radiopharmaceuticals, radioimaging agents, and uses thereof SLC30A5, SLC40A1, FOLH1 CYP26A1 3944/4885CYP3A4 4624/4885CYP2C19 4504/4885
US-20200095257-A1 RADIOPHARMACEUTICALS, RADIOIMAGING AGENTS, AND USES THEREOF SLC30A5, SLC40A1, FOLH1 CYP26A1 3944/4885CYP3A4 4624/4885CYP2C19 4504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.