SCHEMBL21881882

SCHEMBL21881882

CP(C)(=O)c1cccc(-c2cccc(-c3c4ccc5ccccc5c4nc4c3ccc3ccccc34)c2)c1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MAOA P21397 1/20 0.35
ESR1 P03372 3/20 0.34
ESR2 Q92731 2/20 0.33
CYP1A1 P04798 2/20 0.33
CYP1B1 Q16678 2/20 0.33
CMA1 P23946 1/20 0.32
ATM Q13315 1/20 0.32
FBP1 P09467 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
CYP1A2 P05177 2/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
NR1H2 P55055 1/20 0.30
NR1H3 Q13133 1/20 0.30
POLR1A O95602 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18892984 0.97 MAPT (0.39) MAPTL3MBTL1MAOAESR1ESR2
SCHEMBL21882053 0.94 MAPT (0.37) MAPTL3MBTL1MAOAESR1ESR2
SCHEMBL18904710 0.93 HSD17B1 (0.34) MAPTL3MBTL1MAOAESR1ESR2
SCHEMBL21922888 0.91 MAOA (0.37) MAPTL3MBTL1MAOAESR1ESR2
SCHEMBL18892980 0.91 MAPT (0.37) MAPTL3MBTL1MAOAESR1ESR2
SCHEMBL18892965 0.90 MAOA (0.42) MAPTL3MBTL1MAOAESR1ESR2
SCHEMBL21922951 0.88 MAOA (0.39) MAPTL3MBTL1MAOAESR1ESR2
SCHEMBL21922947 0.87 MAOA (0.36) MAPTL3MBTL1MAOAESR1ESR2
SCHEMBL20081091 0.84 MAPT (0.45) MAPTL3MBTL1MAOAESR1ESR2
SCHEMBL17644240 0.84 TOP1 (0.36) MAPTL3MBTL1MAOAESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795186-B2 Organic electronic device comprising an organic semiconductor layer and a device NOVALED GMBH (DE) 2023-10-24 US disclosed
US-11795186-B2 Organic electronic device comprising an organic semiconductor layer and a device NOVALED GMBH (DE) 2023-10-24 US disclosed
EP-3381068-B1 ORGANIC SEMICONDUCTIVE LAYER COMPRISING PHOSPHINE OXIDE COMPOUNDS NOVALED GMBH (DE) 2021-12-22 EP disclosed
US-20200095269-A1 Organic Electronic Device Comprising an Organic Semiconductor Layer and a Device NOVALED GMBH (DE) 2020-03-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200095269-A1 Organic Electronic Device Comprising an Organic Semiconductor Layer and a Device C1S, C1R, CCNA1 MAPT 4555/4885L3MBTL1 812/4885MAOA 1320/4885
US-11795186-B2 Organic electronic device comprising an organic semiconductor layer and a device C1S, C1R, CCNA1 MAPT 4555/4885L3MBTL1 812/4885MAOA 1320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.