SCHEMBL21881901

SCHEMBL21881901

CP(C)(=O)c1cccc(-c2cccc(-c3nc(-c4ccc5ccccc5c4)nc(-c4ccc5ccccc5c4)n3)c2)c1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 12/20 0.43
HSD17B1 P14061 1/20 0.42
HSD17B2 P37059 1/20 0.42
CYP17A1 P05093 1/20 0.41
CYP19A1 P11511 1/20 0.41
CYP11B1 P15538 1/20 0.41
CYP11B2 P19099 1/20 0.41
PLAU P00749 2/20 0.40
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
TP53 P04637 1/20 0.38
CYP1A2 P05177 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HSD17B10 Q99714 1/20 0.38
GSTP1 P09211 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22019468 0.89 L3MBTL1 (0.38) KDM4EMEN1ALDH1A1KMT2A
SCHEMBL21881785 0.88 L3MBTL1 (0.44) KDM4EMEN1ALDH1A1KMT2A
SCHEMBL21881903 0.88 HDAC8 (0.41) KDM4EMEN1ALDH1A1KMT2A
SCHEMBL18904712 0.88 L3MBTL1 (0.44) KDM4EMEN1ALDH1A1KMT2A
SCHEMBL21881783 0.85 L3MBTL1 (0.42) KDM4EMEN1ALDH1A1KMT2A
SCHEMBL21881772 0.85 MEN1 (0.41) SIRT2HSD17B1HSD17B2CYP17A1CYP19A1
SCHEMBL18904885 0.84 HSD17B1 (0.41) SIRT2HSD17B1HSD17B2CYP17A1CYP19A1
SCHEMBL22019263 0.84 GRM5 (0.39) KDM4EMEN1ALDH1A1KMT2A
SCHEMBL24991754 0.82 KDM4E (0.44) SIRT2HSD17B1HSD17B2CYP17A1CYP19A1
SCHEMBL21636468 0.82 L3MBTL1 (0.56) KDM4EMEN1ALDH1A1CYP1A2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795186-B2 Organic electronic device comprising an organic semiconductor layer and a device NOVALED GMBH (DE) 2023-10-24 US disclosed
US-11795186-B2 Organic electronic device comprising an organic semiconductor layer and a device NOVALED GMBH (DE) 2023-10-24 US disclosed
EP-4135060-A2 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS COMPRISING LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2023-02-15 EP disclosed
US-20200095269-A1 Organic Electronic Device Comprising an Organic Semiconductor Layer and a Device NOVALED GMBH (DE) 2020-03-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200095269-A1 Organic Electronic Device Comprising an Organic Semiconductor Layer and a Device C1S, C1R, CCNA1 SIRT2 3660/4885HSD17B1 613/4885HSD17B2 962/4885
US-11795186-B2 Organic electronic device comprising an organic semiconductor layer and a device C1S, C1R, CCNA1 SIRT2 3660/4885HSD17B1 613/4885HSD17B2 962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.