Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30366693 | 0.89 | LMNA (0.49) | EGFRPDGFRBKDRHDAC8HDAC6 | |
| SCHEMBL21834371 | 0.85 | HDAC11 (0.61) | EGFRPDGFRBKDRHDAC8HDAC6 | |
| SCHEMBL30444040 | 0.85 | HDAC11 (0.61) | EGFRPDGFRBKDRHDAC8HDAC6 | |
| SCHEMBL30367171 | 0.81 | POLB (0.48) | EGFRPDGFRBKDRGAALMNA | |
| SCHEMBL30367104 | 0.77 | CYP1A2 (0.50) | NCF1EGFRPDGFRBKDRCYP1A2 | |
| SCHEMBL30367038 | 0.77 | CYP1A2 (0.50) | NCF1EGFRPDGFRBKDRLMNA | |
| SCHEMBL30367213 | 0.76 | CYP1A2 (0.49) | NCF1EGFRPDGFRBKDRLMNA | |
| SCHEMBL30945030 | 0.74 | BACE1 (0.47) | EGFRPDGFRBKDRHDAC8HDAC6 | |
| SCHEMBL29230150 | 0.74 | BACE1 (0.47) | EGFRPDGFRBKDRHDAC8HDAC6 | |
| SCHEMBL24224674 | 0.74 | HDAC8 (0.62) | EGFRPDGFRBKDRHDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3853208-B1 | DRUG CONJUGATE COMPRISING QUINOLINE DERIVATIVES | CENTRE NAT RECH SCIENT (FR) | 2023-06-07 | — | — | EP | disclosed |
| US-20220023435-A1 | DRUG CONJUGATE COMPRISING QUINOLINE DERIVATIVES | Universite Paris-Saclay (FR) | 2022-01-27 | — | — | US | disclosed |
| WO-2020058290-A1 | DRUG CONJUGATE COMPRISING QUINOLINE DERIVATIVES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2020-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220023435-A1 | DRUG CONJUGATE COMPRISING QUINOLINE DERIVATIVES | HRH3, ABCC3, ORC3 | NCF1 1366/4885EGFR 1081/4885PDGFRB 4053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.