Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 3/20 | 0.45 |
| ▸ | GAK | O14976 | 1/20 | 0.45 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.45 |
| ▸ | STK16 | O75716 | 1/20 | 0.45 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.45 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.45 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.45 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30366693 | 0.87 | LMNA (0.49) | LMNAGAATP53TSHRSMN1; SMN2 | |
| SCHEMBL21882934 | 0.81 | NCF1 (0.48) | POLBLMNAGAATP53TSHR | |
| SCHEMBL6592363 | 0.81 | SMN1; SMN2 (0.46) | POLBRAD52LMNAGAATP53 | |
| SCHEMBL2257287 | 0.79 | PDGFRB (0.70) | POLBRAD52EGFRPDGFRBPDGFRA | |
| SCHEMBL30367104 | 0.77 | CYP1A2 (0.50) | KDM1AEGFRPDGFRBKDRCYP1A2 | |
| SCHEMBL30367038 | 0.77 | CYP1A2 (0.50) | LMNATP53TSHRSMN1; SMN2KDM1A | |
| SCHEMBL30367213 | 0.76 | CYP1A2 (0.49) | LMNATSHRSMN1; SMN2KDM1AEGFR | |
| SCHEMBL6790532 | 0.73 | CYP1A2 (0.60) | KDM1ACYP1A2 | |
| SCHEMBL266444 | 0.73 | LMNA (0.64) | POLBLMNAGAATP53TSHR | |
| SCHEMBL29877118 | 0.73 | LMNA (0.64) | POLBLMNAGAATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111825610-B | 2-methylquinoline derivative with anti-tumor activity and synthesis method and application thereof | 中国药科大学 | 2023-03-31 | — | — | CN | disclosed |