Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 5/20 | 0.51 |
| ▸ | NOS3 | P29474 | 3/20 | 0.51 |
| ▸ | NOS1 | P29475 | 3/20 | 0.51 |
| ▸ | CTSC | P53634 | 5/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 7/20 | 0.46 |
| ▸ | MC5R | P33032 | 3/20 | 0.46 |
| ▸ | MC3R | P41968 | 2/20 | 0.46 |
| ▸ | MC1R | Q01726 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449032 | 0.90 | KMT2A (0.54) | CTSCDPP4CTSKKCNH2 | |
| SCHEMBL21883031 | 0.89 | CTSC (0.50) | NOS2CTSCDPP4CTSKKCNH2 | |
| SCHEMBL26510556 | 0.88 | CTSC (0.63) | CTSCDPP4 | |
| Hydrochloric Acid SCHEMBL10520878 | 0.87 | CTSC (0.61) | CTSCDPP4 | |
| Hydrochloric Acid SCHEMBL7271124 | 0.87 | CTSC (0.61) | CTSCDPP4 | |
| Hydrochloric Acid SCHEMBL10520881 | 0.87 | CTSC (0.61) | CTSCDPP4 | |
| SCHEMBL22503593 | 0.87 | CTSC (0.55) | CTSCMC4RMC5RMC3RMC1R | |
| SCHEMBL6367722 | 0.87 | CTSC (0.55) | CTSCMC4RMC5RMC3RMC1R | |
| SCHEMBL29413760 | 0.85 | CTSC (0.59) | CTSCCTSKKCNH2 | |
| SCHEMBL13974141 | 0.84 | CTSC (0.58) | CTSCDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10961266-B2 | Chemoselective methylene hydroxylation in aromatic molecules | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2021-03-30 | — | — | US | disclosed |
| US-20200087331-A1 | CHEMOSELECTIVE METHYLENE HYDROXYLATION IN AROMATIC MOLECULES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2020-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10961266-B2 | Chemoselective methylene hydroxylation in aromatic molecules | PAH, DBH, AHR | NOS2 2276/4885NOS3 563/4885NOS1 2741/4885 |
| US-20200087331-A1 | CHEMOSELECTIVE METHYLENE HYDROXYLATION IN AROMATIC MOLECULES | PAH, DBH, AHR | NOS2 2276/4885NOS3 563/4885NOS1 2741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.