Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29649399 | 0.86 | KMT2A (0.63) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL30147511 | 0.86 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL19954507 | 0.82 | SIRT2 (0.53) | ALDH1A1MAPTKDM4EHDAC6NPC1 | |
| SCHEMBL22930890 | 0.82 | HDAC8 (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL3440249 | 0.81 | HDAC6 (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL19231579 | 0.80 | NPC1 (0.58) | ALDH1A1SMN1; SMN2HPGDMAPTKDM4E | |
| SCHEMBL26076991 | 0.80 | KMT2A (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL24042359 | 0.78 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL21261789 | 0.78 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL23077104 | 0.78 | HDAC6 (0.52) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2707035-B1 | PRETARGETING KIT FOR IMAGING OR THERAPY COMPRISING A TRANS-CYCLOOCTENE DIENOPHILE AND A DIENE | TAGWORKS PHARMACEUTICALS B V (NL) | 2020-04-01 | — | — | EP | disclosed |