SCHEMBL3440249

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23077104	0.95	HDAC6 (0.52)	HDAC6HRH3MEN1KMT2AHDAC8
	SCHEMBL30147511	0.84	ALDH1A1 (0.61)	HDAC6HRH3MEN1KMT2AHDAC8
	SCHEMBL29649399	0.84	KMT2A (0.63)	HDAC6HRH3MEN1KMT2AHDAC8
	SCHEMBL1790900	0.82	HDAC6 (0.47)	HDAC6HRH3MEN1KMT2AHDAC8
	SCHEMBL26484688	0.81	HDAC6 (0.51)	HDAC6HDAC8HDAC3HDAC1DRD1
	SCHEMBL21883070	0.81	ALDH1A1 (0.50)	HDAC6HRH3MEN1KMT2AHDAC8
	SCHEMBL1790897	0.81	HRH3 (0.76)	HDAC6HRH3
	SCHEMBL13928814	0.81	NPC1 (0.56)	HDAC6ALDH1A1LMNAMAPTHPGD
	SCHEMBL3440252	0.81	ALDH1A1 (0.67)	HDAC6MEN1KMT2AKDM4EALDH1A1
	SCHEMBL23077074	0.81	ACHE (0.46)	MEN1KMT2AMAPTSMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.