Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24221920 | 0.79 | NPC1 (0.46) | SMN1; SMN2LMNANPC1NPSR1MAPT | |
| SCHEMBL21883139 | 0.74 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNANPC1NPSR1MAPT | |
| SCHEMBL21883516 | 0.72 | MEN1 (0.50) | SMN1; SMN2LMNANPC1NPSR1MAPT | |
| SCHEMBL21883512 | 0.72 | PLAU (0.48) | SMN1; SMN2LMNANPC1NPSR1MAPT | |
| SCHEMBL24221942 | 0.69 | MEN1 (0.48) | SMN1; SMN2LMNANPC1NPSR1MAPT | |
| SCHEMBL21883129 | 0.69 | MEN1 (0.46) | SMN1; SMN2LMNANPC1NPSR1MAPT | |
| SCHEMBL21883285 | 0.69 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNANPC1NPSR1MAPT | |
| SCHEMBL21883502 | 0.67 | ALDH1A1 (0.46) | SMN1; SMN2LMNANPSR1MAPTMEN1 | |
| SCHEMBL21883504 | 0.66 | RAB9A (0.35) | SMN1; SMN2LMNANPC1MAPTMEN1 | |
| SCHEMBL21807645 | 0.66 | MAPT (0.47) | SMN1; SMN2LMNANPC1NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020061412-A1 | COMPOUNDS WITH COPPER- OR ZINC-ACTIVATED TOXICITY AGAINST MICROBIAL INFECTION | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2020-03-26 | — | — | WO | disclosed |