Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.38 |
| ▸ | NPY4R | P50391 | 6/20 | 0.38 |
| ▸ | NPY1R | P25929 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 2/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13884203 | 0.93 | ADAM10 (0.39) | SIRT2SIRT1SIRT3SIRT5NPY4R | |
| SCHEMBL21897675 | 0.89 | NPY4R (0.41) | SIRT2SIRT1SIRT3SIRT5NPY4R | |
| SCHEMBL18431308 | 0.89 | FURIN (0.41) | SIRT2SIRT1SIRT3SIRT5NPC1 | |
| SCHEMBL24094770 | 0.88 | SIRT2 (0.44) | SIRT2SIRT1SIRT3SIRT5NPY4R | |
| SCHEMBL22507679 | 0.87 | SIRT2 (0.43) | SIRT2SIRT1SIRT3SIRT5NPY4R | |
| SCHEMBL14887385 | 0.87 | SIRT2 (0.43) | SIRT2SIRT1SIRT3SIRT5NPY4R | |
| SCHEMBL17236056 | 0.87 | SIRT2 (0.43) | SIRT2SIRT1SIRT3SIRT5NPY4R | |
| SCHEMBL10051252 | 0.87 | SIRT2 (0.43) | SIRT2SIRT1SIRT3SIRT5NPY4R | |
| SCHEMBL20442348 | 0.87 | SIRT2 (0.45) | SIRT2SIRT1SIRT3SIRT5NPY4R | |
| SCHEMBL18823483 | 0.87 | SIRT2 (0.43) | SIRT2SIRT1SIRT3SIRT5NPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020058290-A1 | DRUG CONJUGATE COMPRISING QUINOLINE DERIVATIVES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2020-03-26 | — | — | WO | disclosed |