Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QRFPR | Q96P65 | 5/20 | 0.55 |
| ▸ | NPY4R | P50391 | 7/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.49 |
| ▸ | NPY1R | P25929 | 5/20 | 0.49 |
| ▸ | NPY2R | P49146 | 3/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.46 |
| ▸ | CHRNG | P07510 | 1/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.46 |
| ▸ | CHRND | Q07001 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30121028 | 0.89 | QRFPR (0.56) | QRFPRNPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL29590985 | 0.89 | QRFPR (0.56) | QRFPRNPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL29591802 | 0.89 | QRFPR (0.54) | QRFPRNPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL29590479 | 0.88 | QRFPR (0.53) | QRFPRNPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL24713048 | 0.87 | QRFPR (0.53) | QRFPRNPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL29630348 | 0.87 | QRFPR (0.53) | QRFPRNPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL29624352 | 0.87 | NPY4R (0.57) | QRFPRNPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL29590419 | 0.87 | QRFPR (0.60) | QRFPRNPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL31462118 | 0.86 | QRFPR (0.62) | QRFPRNPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL30692729 | 0.85 | GNPAT (0.54) | QRFPRNPY4RNPY5RNPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020056249-A1 | ORAL FORMULATIONS OF KAPPA OPIOID RECEPTOR AGONISTS | CARA THERAPEUTICS, INC. (US) | 2020-03-19 | — | — | WO | disclosed |