SCHEMBL21883869

SCHEMBL21883869

COC(=O)C(C)(C)C(=O)Cl

nearest known ligand 0.54

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.54
ELANE P08246 1/20 0.35
KCNN4 O15554 1/20 0.33
ALDH1A1 P00352 1/20 0.33
SRC P12931 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL808799 0.82 DGAT1 (0.74) DGAT1ELANEKCNN4ALDH1A1SRC
SCHEMBL27905901 0.79 DGAT1 (0.70) DGAT1ELANEKCNN4ALDH1A1SRC
Ammonia Solution, Strong SCHEMBL7639328 0.79 DGAT1 (0.70) DGAT1ELANEKCNN4ALDH1A1SRC
SCHEMBL23091415 0.79 DGAT1 (0.70) DGAT1ELANEKCNN4ALDH1A1SRC
Iodide SCHEMBL10533676 0.79 DGAT1 (0.70) DGAT1ELANEKCNN4ALDH1A1SRC
SCHEMBL1464979 0.79 DGAT1 (0.50) DGAT1ELANEKCNN4ALDH1A1
SCHEMBL18269834 0.78 DGAT1 (0.42) DGAT1KCNN4ALDH1A1SRC
SCHEMBL20257642 0.77 DGAT1 (0.48) DGAT1ELANEKCNN4
SCHEMBL5859056 0.77 DGAT1 (0.59) DGAT1ELANEKCNN4ALDH1A1SRC
SCHEMBL808933 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250230154-A1 COMPOUND HAVING SHP2 PROTEIN DEGRADING ACTIVITY, AND MEDICAL USES THEREOF UBIX THERAPEUTICS, INC. (KR) 2025-07-17 US disclosed
EP-4385991-A1 COMPOUND HAVING SHP2 PROTEIN DEGRADING ACTIVITY, AND MEDICAL USES THEREOF Ubix Therapeutics, Inc. (KR) 2024-06-19 EP disclosed
CN-117881678-A Compound with SHP2 protein degradation activity and medical application thereof 尤比克斯治疗公司 2024-04-12 CN disclosed
US-11912714-B2 Spiropyrrolidine derived antiviral agents ENANTA PHARMACEUTICALS, INC. (US) 2024-02-27 US disclosed
WO-2023086352-A1 NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS ENANTA PHARMACEUTICALS, INC. (US) 2023-05-19 WO disclosed
US-20230151019-A1 NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS ENANTA PHARMACEUTICALS, INC. 2023-05-18 US disclosed
WO-2023018155-A1 COMPOUND HAVING SHP2 PROTEIN DEGRADING ACTIVITY, AND MEDICAL USES THEREOF 주식회사 유빅스테라퓨틱스 2023-02-16 WO disclosed
WO-2020071798-A1 COMPOUND, COLORED RESIN COMPOSITION, COLOR FILTER, AND DISPLAY DEVICE 동우 화인켐 주식회사 2020-04-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250230154-A1 COMPOUND HAVING SHP2 PROTEIN DEGRADING ACTIVITY, AND MEDICAL USES THEREOF PTPN1, PTPN5, PTPN2 DGAT1 2063/4885ELANE 1787/4885KCNN4 4792/4885
US-20230151019-A1 NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS ACE, ACE2, PKD1 DGAT1 3619/4885ELANE 3860/4885KCNN4 474/4885
US-11912714-B2 Spiropyrrolidine derived antiviral agents ACE, ACE2, PKD1 DGAT1 3863/4885ELANE 3520/4885KCNN4 331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.