Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.74 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL7639328 | 0.97 | DGAT1 (0.70) | DGAT1ELANEALDH1A1KCNN4TSHR | |
| Iodide SCHEMBL10533676 | 0.97 | DGAT1 (0.70) | DGAT1ELANEALDH1A1KCNN4TSHR | |
| SCHEMBL23091415 | 0.97 | DGAT1 (0.70) | DGAT1ELANEALDH1A1KCNN4TSHR | |
| SCHEMBL5859056 | 0.87 | DGAT1 (0.59) | DGAT1ELANEALDH1A1KCNN4TSHR | |
| SCHEMBL10814852 | 0.86 | DGAT1 (0.58) | DGAT1ELANEALDH1A1KCNN4 | |
| SCHEMBL1735445 | 0.86 | DGAT1 (1.00) | DGAT1ELANEALDH1A1KCNN4GAA | |
| SCHEMBL1022153 | 0.84 | DGAT1 (0.56) | DGAT1ELANEALDH1A1KCNN4TSHR | |
| SCHEMBL1010735 | 0.84 | DGAT1 (0.56) | DGAT1ELANEALDH1A1KCNN4TSHR | |
| SCHEMBL21883869 | 0.82 | DGAT1 (0.54) | DGAT1ELANEALDH1A1KCNN4SRC | |
| SCHEMBL18778754 | 0.82 | DGAT1 (0.54) | DGAT1ELANEALDH1A1KCNN4SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114605622-B | Aliphatic polyester with malonic acid structure, and preparation method and application thereof | 苏州瀚海新材料有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-115057775-A | Preparation method of dimethyl 2, 2-dimethylmalonate | 临海市建新化工有限公司 | 2022-09-16 | — | — | CN | claimed |
| CN-114605622-A | Aliphatic polyester with malonic acid structure and preparation method and application thereof | 苏州瀚海新材料有限公司 | 2022-06-10 | — | — | CN | claimed |
| CN-108285517-B | Graphene/ester ether copolymerization type thermosetting polyurethane composite material and preparation method thereof | 化州市联合民生轮业有限公司 | 2021-08-20 | — | — | CN | claimed |
| CN-106245148-A | A kind of original liquid coloring anophelifuge polyester fiber | 福建经纬新纤科技实业有限公司 | 2016-12-21 | — | — | CN | claimed |
| CN-103508888-A | Synthetic method of 2,2-dimethyl dimethylmalonate | BEIJING INST PETROCHEM TECH | 2014-01-15 | — | — | CN | claimed |
| US-6415614-B1 | CONTROLLING VAPOR PRESSURE OF MIXTURE | VISTEON GLOBAL TECHNOLOGIES, INC. | 2002-07-09 | — | — | US | claimed |
| US-6045950-A | A LITHIUM BATTERY CONTAINING AN ELECTROLYTE CONTAINING A MALONATE ESTER HAVING NO ALPHA-CARBON HYDROGEN ATOMS; A CATHODE THAT BECOMES LITHIATED DURING DISCHARGE OF LITHIUM BATTERY, AN ANODE AND A SEPARATOR BETWEEN ANODE AND CATHODE | DURACELL INC. (US) | 2000-04-04 | — | — | US | claimed |
| WO-2000001027-A1 | SOLVENT FOR ELECTROLYTIC SOLUTIONS | DURACELL INC. (US) | 2000-01-06 | — | — | WO | claimed |
| US-4046817-A | Method of synthesis of pyrogallol | IMC CHEMICAL GROUP, INC. (US) | 1977-09-06 | — | — | US | claimed |
| US-12637680-B2 | Recombinant host cells for the production of malonate | LYGOS, INC. (US) | 2026-05-26 | — | — | US | disclosed |
| CN-119709450-A | Recombinant host cells for malonate production | 利戈斯股份有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-114616330-B | Recombinant host cells for malonate production | 利戈斯股份有限公司 | 2025-01-03 | — | — | CN | disclosed |
| US-20240191216-A1 | RECOMBINANT HOST CELLS FOR THE PRODUCTION OF MALONATE | LYGOS, INC. (US) | 2024-06-13 | — | — | US | disclosed |
| CN-118086086-A | Recombinant host cells for malonate production | 利戈斯股份有限公司 | 2024-05-28 | — | — | CN | disclosed |
| US-4647573-A | 7-oxabicycloheptane substituted thioamide-amide prostaglandin analogs | E. R. SQUIBB & SONS, INC. (US) | 1987-03-03 | — | — | US | disclosed |
| EP-0210664-A2 | 7-oxabicycloheptane substituted diacid diamide prostaglandin analogs | E.R. Squibb & Sons, Inc. (US) | 1987-02-04 | — | — | EP | disclosed |
| US-4213992-A | Insecticidal carbamates | BASF AKTIENGESELLSCHAFT (DE) | 1980-07-22 | — | — | US | disclosed |
| US-4092351-A | Method of synthesis of 4,5,6-trihydroxyisophthalic acid | IMC CHEMICAL GROUP, INC. (US) | 1978-05-30 | — | — | US | disclosed |
| US-4046817-A | Method of synthesis of pyrogallol | IMC CHEMICAL GROUP, INC. (US) | 1977-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12637680-B2 | Recombinant host cells for the production of malonate | DCXR, ETV1, LYPLA2 | DGAT1 387/4885ELANE 2986/4885ALDH1A1 1554/4885 |
| US-20240191216-A1 | RECOMBINANT HOST CELLS FOR THE PRODUCTION OF MALONATE | ME1, MAL2, ME3 | DGAT1 1582/4885ELANE 4132/4885ALDH1A1 2274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.