Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15490004 | 0.70 | ABCB1 (0.43) | HSD11B1BRD4GPR119 | |
| SCHEMBL678742 | 0.68 | — | — | |
| SCHEMBL21889156 | 0.68 | — | — | |
| SCHEMBL443319 | 0.65 | HSD11B1 (0.38) | HSD11B1GPR119 | |
| SCHEMBL15110040 | 0.65 | HSD11B1 (0.35) | HSD11B1BRD4GPR119 | |
| SCHEMBL15932025 | 0.64 | GPR119 (0.37) | HSD11B1GPR119 | |
| SCHEMBL7655000 | 0.63 | HSD11B1 (0.36) | HSD11B1BRD4GPR119 | |
| SCHEMBL23791572 | 0.63 | — | — | |
| SCHEMBL1091053 | 0.62 | NOTUM (0.40) | HSD11B1GPR119 | |
| SCHEMBL7602702 | 0.62 | KDM4E (0.35) | HSD11B1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3255044-B1 | DIAZA-BENZOFLUORANTHRENE COMPOUNDS | HARBIN PHARMACEUTICAL GROUP CO LTD GENERAL PHARMACEUTICAL FACTORY (CN) | 2020-04-01 | — | — | EP | disclosed |