SCHEMBL2188453

SCHEMBL2188453

CCCCCCCCCC(CCCCCCC)COCC(CCCCCCC)CCCCCCCCC

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.54
CYP3A4 P08684 2/20 0.45
TSHR P16473 1/20 0.42
THRB P10828 1/20 0.42
DNM1 Q05193 2/20 0.42
ALDH1A1 P00352 1/20 0.41
OPRM1 P35372 1/20 0.40
PRSS1 P07477 1/20 0.40
PRSS2 P07478 1/20 0.40
PRSS3 P35030 1/20 0.40
SMPD1 P17405 3/20 0.39
USP2 O75604 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
GPR84 Q9NQS5 2/20 0.38
FDPS P14324 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1776413 1.00 LMNA (0.54) LMNACYP3A4TSHRTHRBDNM1
SCHEMBL8387794 1.00 LMNA (0.54) LMNACYP3A4TSHRTHRBDNM1
SCHEMBL9509191 1.00 LMNA (0.54) LMNACYP3A4TSHRTHRBDNM1
SCHEMBL20394323 1.00 LMNA (0.54) LMNACYP3A4TSHRTHRBDNM1
SCHEMBL18327083 1.00 LMNA (0.54) LMNACYP3A4TSHRTHRBDNM1
SCHEMBL1776604 1.00 LMNA (0.54) LMNACYP3A4TSHRTHRBDNM1
SCHEMBL574982 1.00 LMNA (0.54) LMNACYP3A4TSHRTHRBDNM1
SCHEMBL20253212 1.00 LMNA (0.54) LMNACYP3A4TSHRTHRBDNM1
SCHEMBL21641724 1.00 LMNA (0.54) LMNACYP3A4TSHRTHRBDNM1
SCHEMBL9233922 1.00 LMNA (0.54) LMNACYP3A4TSHRTHRBDNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024142920-A1 OIL-IN-WATER EMULSION COSMETIC 株式会社 資生堂 2024-07-04 WO disclosed
CN-108743410-B Liquid cosmetic 株式会社资生堂 2023-07-21 CN disclosed
US-20200239801-A1 ETHER COMPOUNDS AND RELATED COMPOSITIONS CASTROL LTD (GB) 2020-07-30 US disclosed
US-10669499-B2 Ether compounds and related compositions CASTROL LIMITED (GB) 2020-06-02 US disclosed
US-20200115651-A1 Ether-Based Lubricant Compositions, Methods and Uses CASTROL LIMITED (GB) 2020-04-16 US disclosed
US-20200102521-A1 Ether-Based Lubricant Compositions, Methods and Uses CASTROL LIMITED (GB) 2020-04-02 US disclosed
EP-3351611-A1 REFRIGERATION MACHINE OIL, COMPOSITION FOR REFRIGERATION MACHINES, AND COMPRESSION-TYPE REFRIGERATION MACHINE Idemitsu Kosan Co., Ltd (JP) 2018-07-25 EP disclosed
US-20180163150-A1 ETHER COMPOUNDS AND RELATED COMPOSITIONS CASTROL LIMITED (GB) 2018-06-14 US disclosed
US-20180163150-A1 ETHER COMPOUNDS AND RELATED COMPOSITIONS CASTROL LIMITED (GB) 2018-06-14 US disclosed
EP-1905505-B1 Methods of manufacturing emulsions FUJIFILM CORP (JP) 2011-07-13 EP disclosed
EP-1987809-A1 Oil-in-water type emulsion composition enthaltend Retinoide Shiseido Co., Ltd. (JP) 2008-11-05 EP disclosed
US-20080081842-A1 EMULSION AND METHOD OF MANUFACTURING EMULSION FUJIFILM CORPORATION (JP) 2008-04-03 US disclosed
EP-1905505-A2 Method of manufacturing an emulsion, and emulsion so produced FUJIFILM Corporation (JP) 2008-04-02 EP disclosed
US-6210693-B1 CONTAINING A VITAMIN A FATTY ACID ESTER, WHICH FURTHER CONTAINS AN OIL SOLUBLE ANITOXIDANT AND A HYDROPHILIC NONIONIC SURFACTANT FOR PREVENTING HYDROLYSIS SHISEIDO COMPANY, LTD. (JP) 2001-04-03 US disclosed
EP-0985404-A1 OIL-IN-WATER TYPE EMULSIFIED COMPOSITIONS SHISEIDO COMPANY LIMITED (JP) 2000-03-15 EP disclosed
EP-0535367-A2 Emulsified hair cosmetic composition Kao Corporation (JP) 1993-04-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10669499-B2 Ether compounds and related compositions C9, CNR2, CNR1 LMNA 494/4885CYP3A4 1874/4885TSHR 3902/4885
US-20200239801-A1 ETHER COMPOUNDS AND RELATED COMPOSITIONS C9, CNR2, CNR1 LMNA 494/4885CYP3A4 1874/4885TSHR 3902/4885
US-20180163150-A1 ETHER COMPOUNDS AND RELATED COMPOSITIONS C9, CNR2, CNR1 LMNA 494/4885CYP3A4 1874/4885TSHR 3902/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.