SCHEMBL1776604

SCHEMBL1776604

CCCCCCCCCCCCCC(CCCCCCCCCC)COCC(CCCCCCCCCC)CCCCCCCCCCCCC

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.54
CYP3A4 P08684 2/20 0.45
TSHR P16473 1/20 0.42
THRB P10828 1/20 0.42
DNM1 Q05193 2/20 0.42
ALDH1A1 P00352 1/20 0.41
OPRM1 P35372 1/20 0.40
PRSS1 P07477 1/20 0.40
PRSS2 P07478 1/20 0.40
PRSS3 P35030 1/20 0.40
SMPD1 P17405 3/20 0.39
USP2 O75604 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
GPR84 Q9NQS5 2/20 0.38
FDPS P14324 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1776413 1.00 LMNA (0.54) LMNACYP3A4TSHRTHRBDNM1
SCHEMBL8387794 1.00 LMNA (0.54) LMNACYP3A4TSHRTHRBDNM1
SCHEMBL9509191 1.00 LMNA (0.54) LMNACYP3A4TSHRTHRBDNM1
SCHEMBL2188453 1.00 LMNA (0.54) LMNACYP3A4TSHRTHRBDNM1
SCHEMBL20394323 1.00 LMNA (0.54) LMNACYP3A4TSHRTHRBDNM1
SCHEMBL18327083 1.00 LMNA (0.54) LMNACYP3A4TSHRTHRBDNM1
SCHEMBL574982 1.00 LMNA (0.54) LMNACYP3A4TSHRTHRBDNM1
SCHEMBL20253212 1.00 LMNA (0.54) LMNACYP3A4TSHRTHRBDNM1
SCHEMBL21641724 1.00 LMNA (0.54) LMNACYP3A4TSHRTHRBDNM1
SCHEMBL9233922 1.00 LMNA (0.54) LMNACYP3A4TSHRTHRBDNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111032000-B Water-in-oil type emulsified cosmetic 株式会社资生堂 2024-02-06 CN disclosed
CN-108743410-B Liquid cosmetic 株式会社资生堂 2023-07-21 CN disclosed
US-20210077378-A1 WATER-IN-OIL TYPE EMULSION COSMETIC SHISEIDO COMPANY, LTD. (JP) 2021-03-18 US disclosed
EP-3677245-A1 WATER-IN-OIL TYPE EMULSION COSMETIC Shiseido Co., Ltd. (JP) 2020-07-08 EP disclosed
CN-111032000-A Water-in-oil type emulsion cosmetic 株式会社资生堂 2020-04-17 CN disclosed
EP-2853572-B1 Water-in-oil emulsified adhesive RISO KAGAKU CORP (JP) 2020-01-22 EP disclosed
EP-1734065-B1 PROCESS FOR PRODUCTION OF PURIFIED LIQUID MEDIUM-CHAIN ALKYL MODIFIED POLYDIMETHYLSILOXANES AND COSMETICS DOW CORNING TORAY CO LTD (JP) 2018-09-12 EP disclosed
EP-2559426-B1 WATER-IN-OIL EMULSION COMPOSITION SHISEIDO CO LTD (JP) 2017-08-02 EP disclosed
US-9034375-B2 Water-in-oil emulsion composition SHISEIDO COMPANY, LTD. (JP) 2015-05-19 US disclosed
EP-2853572-A1 Water-in-oil type emulsion adhesive Riso Kagaku Corporation (JP) 2015-04-01 EP disclosed
EP-1145704-A1 METHOD FOR PRODUCING COSMETICS Shiseido Co., Ltd. (JP) 2001-10-17 EP disclosed
US-6210693-B1 CONTAINING A VITAMIN A FATTY ACID ESTER, WHICH FURTHER CONTAINS AN OIL SOLUBLE ANITOXIDANT AND A HYDROPHILIC NONIONIC SURFACTANT FOR PREVENTING HYDROLYSIS SHISEIDO COMPANY, LTD. (JP) 2001-04-03 US disclosed
US-6150425-A COMPRISING AN OUTER PHASE OIL AND OIL IN WATER EMULSION IN THE INNER PHASE WHICH CONTAINING WATER, AN OIL BASED INGREDIENT, A SURFACTANT AND AN AMPHIPHILIC SUBSTANCE; PREPARED BY A HIGH PRESSURE OR ULTRASONIC EMULSIFICATION SHISEIDO COMPANY, LTD. (JP) 2000-11-21 US disclosed
EP-0985404-A1 OIL-IN-WATER TYPE EMULSIFIED COMPOSITIONS SHISEIDO COMPANY LIMITED (JP) 2000-03-15 EP disclosed
EP-0970741-A1 O/W/O TYPE MULTIPHASE EMULSION SHISEIDO COMPANY LIMITED (JP) 2000-01-12 EP disclosed
US-5985177-A STABILIZATION OF OIL-SOLUBLE AGENTS BLENDED IN THE INNER OIL PHASE, ORGANOPHILIC CLAY MINERAL IS AN INCLUSION COMPOUND WHICH IS FORMED BY CATION EXCHANGE REACTION BETWEEN A WATER SWELLABLE-CLAY MINERAL AND A QUATERNARY AMMONIUM CATION AND SHISEIDO CO., LTD. (JP) 1999-11-16 US disclosed
EP-0782846-A2 O/W/O type multiple emulsion and method of preparing the same SHISEIDO COMPANY LIMITED (JP) 1997-07-09 EP disclosed
EP-0535367-A2 Emulsified hair cosmetic composition Kao Corporation (JP) 1993-04-07 EP disclosed
US-5015469-A Water swellable clays, cationic surfactants, an alkoxy modified polysiloxane in water SHIDEIDO COMPANY LTD. (JP) 1991-05-14 US disclosed
EP-0331833-A1 Water-in-oil emulsion type cosmetics SHISEIDO COMPANY LIMITED (JP) 1989-09-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210077378-A1 WATER-IN-OIL TYPE EMULSION COSMETIC CUTA, LRBA, SLTM LMNA 327/4885CYP3A4 3244/4885TSHR 1589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.