Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23854855 | 0.89 | KDM4E (0.32) | ARPGR | |
| SCHEMBL23854872 | 0.89 | HCRTR1 (0.34) | ARPGRHCRTR1HCRTR2 | |
| SCHEMBL21884793 | 0.86 | MEN1 (0.31) | — | |
| SCHEMBL23854862 | 0.85 | PGR (0.40) | ARPGR | |
| SCHEMBL21884532 | 0.83 | PGR (0.35) | ARPGR | |
| SCHEMBL21884535 | 0.83 | AR (0.35) | ARPGR | |
| SCHEMBL23854850 | 0.82 | SCN9A (0.35) | ARPGRHCRTR1HCRTR2 | |
| SCHEMBL23854839 | 0.81 | MKNK1 (0.32) | — | |
| SCHEMBL21884539 | 0.81 | USP30 (0.34) | — | |
| SCHEMBL21884531 | 0.81 | PDK2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020061473-A1 | SMALL MOLECULES TARGETING MUTANT MAMMALIAN PROTEINS | JNANA THERAPEUTICS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |