Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21884531 | 0.91 | PDK2 (0.32) | — | |
| SCHEMBL23854884 | 0.88 | PDK2 (0.31) | — | |
| SCHEMBL21884532 | 0.87 | PGR (0.35) | MEN1KMT2A | |
| SCHEMBL21884537 | 0.86 | AR (0.31) | — | |
| SCHEMBL21884490 | 0.85 | PIM1 (0.35) | MEN1LMNAGAAHPGDHTT | |
| SCHEMBL21884540 | 0.84 | GAA (0.33) | GAA | |
| SCHEMBL23854864 | 0.84 | — | — | |
| SCHEMBL23854855 | 0.83 | KDM4E (0.32) | LMNAHPGDHTT | |
| SCHEMBL23854839 | 0.82 | MKNK1 (0.32) | GAANISCH | |
| SCHEMBL21884539 | 0.82 | USP30 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020061473-A1 | SMALL MOLECULES TARGETING MUTANT MAMMALIAN PROTEINS | JNANA THERAPEUTICS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |