Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 5/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 7/20 | 0.40 |
| ▸ | ESRRA | P11474 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4581525 | 0.82 | CYP19A1 (0.65) | CYP19A1MAOBMAOAALDH1A1HPGD | |
| SCHEMBL29390509 | 0.82 | CYP19A1 (0.65) | CYP19A1MAOBMAOAALDH1A1HPGD | |
| SCHEMBL23795088 | 0.81 | CYP19A1 (0.50) | CYP19A1MAOBMAOAALDH1A1HPGD | |
| SCHEMBL9472016 | 0.80 | CYP19A1 (0.62) | CYP19A1MAOBMAOAALDH1A1HPGD | |
| SCHEMBL1377229 | 0.80 | CYP19A1 (0.62) | CYP19A1MAOBMAOAALDH1A1HPGD | |
| SCHEMBL12149014 | 0.79 | MAOB (0.63) | CYP19A1MAOBMAOAALDH1A1HPGD | |
| SCHEMBL18170274 | 0.78 | CYP19A1 (0.61) | CYP19A1MAOBMAOAALDH1A1HPGD | |
| SCHEMBL597069 | 0.76 | MAOB (0.46) | CYP19A1MAOBMAOAALDH1A1HPGD | |
| SCHEMBL1374021 | 0.74 | CYP19A1 (0.67) | CYP19A1MAOBMAOAALDH1A1HPGD | |
| SCHEMBL5145150 | 0.74 | CYP19A1 (0.67) | CYP19A1MAOBMAOAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424932-A1 | BORONOPHTHALIDES FOR THERAPEUTIC USE | Anacor Pharmaceuticals, Inc (US) | 2019-01-09 | — | — | EP | disclosed |
| EP-3246034-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | Anacor Pharmaceuticals, Inc. (US) | 2017-11-22 | — | — | EP | disclosed |
| EP-2564857-B1 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS INC (US) | 2017-05-03 | — | — | EP | disclosed |
| EP-2987796-A1 | HALOGEN-SUBSTITUTED BORONOPHTHALIDES FOR THE TREATMENT OF INFECTIONS | Anacor Pharmaceuticals, Inc. (US) | 2016-02-24 | — | — | EP | disclosed |
| EP-2343304-B1 | Biocidal boronophthalide compounds | ANACOR PHARMACEUTICALS INC (US) | 2015-06-10 | — | — | EP | disclosed |
| EP-2564857-A1 | Boron-containing small molecules as anti-inflammatory agents | Anacor Pharmaceuticals, Inc. (US) | 2013-03-06 | — | — | EP | disclosed |
| EP-2343304-A1 | Biocidal boronophthalide compounds | Anacor Pharmaceuticals, Inc. (US) | 2011-07-13 | — | — | EP | disclosed |