SCHEMBL12149014

SCHEMBL12149014

N#Cc1ccc(Oc2ccc(Br)cc2)cc1C#N

nearest known ligand 0.63

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAOB P27338 6/20 0.63
MAOA P21397 4/20 0.63
CYP19A1 P11511 2/20 0.54
ALDH1A1 P00352 2/20 0.51
HPGD P15428 2/20 0.51
NPSR1 Q6W5P4 2/20 0.48
AR P10275 4/20 0.47
PDE4B Q07343 1/20 0.47
MAPT P10636 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9472016 0.90 CYP19A1 (0.62) MAOBMAOACYP19A1ALDH1A1HPGD
SCHEMBL1377229 0.90 CYP19A1 (0.62) MAOBMAOACYP19A1ALDH1A1HPGD
SCHEMBL29390509 0.88 CYP19A1 (0.65) MAOBMAOACYP19A1ALDH1A1HPGD
SCHEMBL4581525 0.88 CYP19A1 (0.65) MAOBMAOACYP19A1ALDH1A1HPGD
SCHEMBL29688449 0.84 ALDH1A1 (0.62) MAOBMAOACYP19A1ALDH1A1HPGD
SCHEMBL1377135 0.84 ALDH1A1 (0.62) MAOBMAOACYP19A1ALDH1A1HPGD
SCHEMBL18170274 0.84 CYP19A1 (0.61) MAOBMAOACYP19A1ALDH1A1HPGD
SCHEMBL9747026 0.82 ALDH1A1 (0.65) MAOBMAOACYP19A1ALDH1A1HPGD
SCHEMBL20511087 0.82 CYP19A1 (0.56) MAOBMAOACYP19A1ALDH1A1HPGD
SCHEMBL523446 0.82 ALDH1A1 (0.65) MAOBMAOACYP19A1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121588908-B Catalyst for in-situ degradation of COD (chemical oxygen demand) of wastewater and preparation method thereof 成都昊宏水处理技术有限公司 2026-05-15 CN claimed
CN-121588908-B Catalyst for in-situ degradation of COD (chemical oxygen demand) of wastewater and preparation method thereof 成都昊宏水处理技术有限公司 2026-05-15 CN disclosed
US-8530607-B2 Aromatic ether and alkynyl containing phthalonitriles THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2013-09-10 US disclosed
US-20110288254-A1 AROMATIC ETHER AND ALKYNYL CONTAINING PHTHALONITRILES THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2011-11-24 US disclosed
US-8039576-B2 Aromatic ether and alkynyl containing phthalonitriles THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2011-10-18 US disclosed
US-20090069484-A1 AROMATIC ETHER AND ALKYNYL CONTAINING PHTHALONITRILES THE GOVERNMENT OF THE US, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2009-03-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110288254-A1 AROMATIC ETHER AND ALKYNYL CONTAINING PHTHALONITRILES PNN, BECN1, ACIN1 MAOB 4135/4885MAOA 4110/4885CYP19A1 3314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.