SCHEMBL4581525

SCHEMBL4581525

N#Cc1ccc(Oc2ccc(C#N)c(C#N)c2)cc1C#N

nearest known ligand 0.65

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.65
ALDH1A1 P00352 2/20 0.56
HPGD P15428 2/20 0.56
PDE4B Q07343 1/20 0.54
MAOB P27338 4/20 0.53
AR P10275 9/20 0.52
NPSR1 Q6W5P4 1/20 0.51
MAOA P21397 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29390509 1.00 CYP19A1 (0.65) CYP19A1ALDH1A1HPGDPDE4BMAOB
SCHEMBL9472016 0.98 CYP19A1 (0.62) CYP19A1ALDH1A1HPGDPDE4BMAOB
SCHEMBL1377229 0.98 CYP19A1 (0.62) CYP19A1ALDH1A1HPGDPDE4BMAOB
SCHEMBL18170274 0.95 CYP19A1 (0.61) CYP19A1ALDH1A1HPGDPDE4BMAOB
SCHEMBL29688449 0.91 ALDH1A1 (0.62) CYP19A1ALDH1A1HPGDPDE4BMAOB
SCHEMBL5145150 0.91 CYP19A1 (0.67) CYP19A1ALDH1A1HPGDPDE4BMAOB
SCHEMBL1374021 0.91 CYP19A1 (0.67) CYP19A1ALDH1A1HPGDPDE4BMAOB
SCHEMBL1377135 0.91 ALDH1A1 (0.62) CYP19A1ALDH1A1HPGDPDE4BMAOB
SCHEMBL31168160 0.91 CYP19A1 (0.67) CYP19A1ALDH1A1HPGDPDE4BMAOB
SCHEMBL9745473 0.89 ALDH1A1 (0.65) CYP19A1ALDH1A1HPGDPDE4BMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3887428-B1 RESIN BLENDS INCLUDING PHTHALONITRILE RESIN AND THIADIAZOLE SUBSTITUTED PHTHALONITRILE COMPOUND, ARTICLES, COMPOUNDS, AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-05-27 EP claimed
US-12291602-B2 Polymerizable compositions including a phthalonitrile resin and a polyoxometalate, articles, and methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-05-06 US claimed
EP-4107217-B1 POLYMERIZABLE COMPOSITIONS INCLUDING A PHTHALONITRILE RESIN AND A POLYOXOMETALATE, ARTICLES, AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-03-27 EP claimed
US-11932750-B2 Resin blends including phthalonitrile resin and thiadiazole substituted phthalonitrile compound, articles, compounds, and methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-03-19 US claimed
CN-113166408-B Resin blends, articles, compounds and methods comprising phthalonitrile resin and thiadiazole substituted phthalonitrile compounds 3M创新有限公司 2023-09-05 CN claimed
CN-115160848-B Preparation method of metal phthalocyanine modified titanium dioxide anti-yellowing agent 西安工业大学 2023-08-18 CN claimed
CN-116376226-A Preparation method and application of high-temperature-resistant epoxy resin material 琼海市淑滨白信息科技有限公司 2023-07-04 CN claimed
US-20230063744-A1 Polymerizable Compositions Including a Phthalonitrile Resin and a Polyoxometalate, Articles, and Methods 3M INNOVATIVE PROPERTIES COMPANY 2023-03-02 US claimed
EP-4107217-A1 POLYMERIZABLE COMPOSITIONS INCLUDING A PHTHALONITRILE RESIN AND A POLYOXOMETALATE, ARTICLES, AND METHODS 3M Innovative Properties Company (US) 2022-12-28 EP claimed
CN-115160848-A Preparation method of metal phthalocyanine modified titanium dioxide anti-yellowing agent 西安工业大学 2022-10-11 CN claimed
CN-115038747-A Polymerizable compositions, articles, and methods comprising phthalonitrile resins and polyoxometallates 3M创新有限公司 2022-09-09 CN claimed
US-20210340355-A1 Resin Blends Including Phthalonitrile Resin and Thiadiazole Substituted Phthalonitrile Compound, Articles, Compounds, and Methods 3M INNOVATIVE PROPERTIES COMPANY 2021-11-04 US claimed
EP-3887428-A1 RESIN BLENDS INCLUDING PHTHALONITRILE RESIN AND THIADIAZOLE SUBSTITUTED PHTHALONITRILE COMPOUND, ARTICLES, COMPOUNDS, AND METHODS 3M Innovative Properties Company (US) 2021-10-06 EP claimed
CN-113166408-A Resin blends, articles, compounds, and methods comprising phthalonitrile resins and thiadiazole-substituted phthalonitrile compounds 3M创新有限公司 2021-07-23 CN claimed
WO-2020109902-A1 RESIN BLENDS INCLUDING PHTHALONITRILE RESIN AND THIADIAZOLE SUBSTITUTED PHTHALONITRILE COMPOUND, ARTICLES, COMPOUNDS, AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-06-04 WO claimed
US-5242755-A Polybis/phthalonitriles/ THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1993-09-07 US claimed
EP-3887428-B1 RESIN BLENDS INCLUDING PHTHALONITRILE RESIN AND THIADIAZOLE SUBSTITUTED PHTHALONITRILE COMPOUND, ARTICLES, COMPOUNDS, AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-05-27 EP disclosed
US-20250250417-A1 CURABLE FLUOROPOLYMER COMPOSITIONS COMPRISING A CATALYST AND A BIS PHTHALONITRILE-CONTAINING COMPOUND AND CURED ARTICLES THEREFROM 3M INNOVATIVE PROPERTIES COMPANY 2025-08-07 US disclosed
US-3972902-A EPOXY RESIN CURING AGENT GENERAL ELECTRIC COMPANY (US) 1976-08-03 US disclosed
US-3956320-A FIREPROOFING GENERAL ELECTRIC COMPANY (US) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11932750-B2 Resin blends including phthalonitrile resin and thiadiazole substituted phthalonitrile compound, articles, compounds, and methods THUMPD1, RBBP5, RB1 CYP19A1 4270/4885ALDH1A1 680/4885HPGD 906/4885
US-20210340355-A1 Resin Blends Including Phthalonitrile Resin and Thiadiazole Substituted Phthalonitrile Compound, Articles, Compounds, and Methods THUMPD1, RBBP5, RB1 CYP19A1 4270/4885ALDH1A1 680/4885HPGD 906/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.