Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 4/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20469142 | 0.95 | FFAR1 (0.35) | PTGER2PRKCZKDM4EMAPTMEN1 | |
| SCHEMBL19186360 | 0.89 | PTGER2 (0.35) | PTGER2KDM4EMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL9607891 | 0.89 | AR (0.36) | PRKCZMAPTMAPK1RAB9AFFAR4 | |
| SCHEMBL23045941 | 0.87 | FFAR1 (0.39) | KDM4EMAPTFFAR1PPARDALDH1A1 | |
| SCHEMBL26144195 | 0.86 | AKR1C3 (0.36) | PRKCZKDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL20469262 | 0.86 | KDM4E (0.36) | KDM4EMAPTNPC1RAB9AKMT2A | |
| SCHEMBL18437003 | 0.86 | FFAR4 (0.35) | PTGER2KDM4EMAPTMEN1NPC1 | |
| SCHEMBL12196858 | 0.85 | AR (0.42) | PRKCZMAPK1RAB9AFFAR1 | |
| SCHEMBL20112831 | 0.85 | MAPT (0.42) | KDM4EMAPTMEN1NPC1TP53 | |
| SCHEMBL18646588 | 0.84 | FFAR1 (0.40) | KDM4EMAPTMEN1NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428246-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2020-04-15 | — | — | EP | disclosed |