Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607892 | 0.88 | ELANE (0.40) | KDM4EALDH1A1TSHRMAPTDGAT1 | |
| SCHEMBL20365886 | 0.88 | ELANE (0.36) | KDM4EALDH1A1LMNATSHRHSD17B10 | |
| SCHEMBL21884911 | 0.86 | PTGER2 (0.36) | KDM4EALDH1A1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL18522596 | 0.86 | KMT2A (0.38) | KDM4EALDH1A1LMNATSHRHSD17B10 | |
| SCHEMBL20469142 | 0.86 | FFAR1 (0.35) | KDM4EHSD17B10SMN1; SMN2MAPTNPC1 | |
| SCHEMBL21165409 | 0.85 | GPR174 (0.40) | KDM4EALDH1A1LMNATSHRHSD17B10 | |
| SCHEMBL19186360 | 0.85 | PTGER2 (0.35) | KDM4EALDH1A1LMNATSHRHSD17B10 | |
| SCHEMBL18437003 | 0.83 | FFAR4 (0.35) | KDM4EALDH1A1LMNATSHRHSD17B10 | |
| SCHEMBL17625770 | 0.82 | TNFSF11 (0.38) | KDM4EALDH1A1TSHRRAB9AELANE | |
| SCHEMBL12196857 | 0.82 | ELANE (0.36) | KDM4EALDH1A1LMNATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10351771-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2019-07-16 | — | — | US | disclosed |
| US-20180223187-A1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | US | disclosed |